ID A3CXZ1_METMJ Unreviewed; 304 AA.
AC A3CXZ1;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Thiamine pyrophosphate enzyme domain protein TPP-binding protein {ECO:0000313|EMBL:ABN58241.1};
GN OrderedLocusNames=Memar_2318 {ECO:0000313|EMBL:ABN58241.1};
OS Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoculleus.
OX NCBI_TaxID=368407 {ECO:0000313|EMBL:ABN58241.1, ECO:0000313|Proteomes:UP000002146};
RN [1] {ECO:0000313|EMBL:ABN58241.1, ECO:0000313|Proteomes:UP000002146}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35101 / DSM 1498 / JR1
RC {ECO:0000313|Proteomes:UP000002146};
RX PubMed=21304656; DOI=10.4056/sigs.32535;
RA Anderson I.J., Sieprawska-Lupa M., Lapidus A., Nolan M., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Saunders E., Han C.,
RA Brettin T., Detter J.C., Bruce D., Mikhailova N., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981
RT type strain JR1.";
RL Stand. Genomic Sci. 1:189-196(2009).
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DR EMBL; CP000562; ABN58241.1; -; Genomic_DNA.
DR AlphaFoldDB; A3CXZ1; -.
DR STRING; 368407.Memar_2318; -.
DR KEGG; mem:Memar_2318; -.
DR eggNOG; arCOG01601; Archaea.
DR HOGENOM; CLU_058423_0_0_2; -.
DR OrthoDB; 296931at2157; -.
DR Proteomes; UP000002146; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd03376; TPP_PFOR_porB_like; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR42897:SF1; 2-OXOACID OXIDOREDUCTASE (FERREDOXIN); 1.
DR PANTHER; PTHR42897; PYRUVATE SYNTHASE SUBUNIT PORB; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
FT DOMAIN 73..210
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
FT REGION 144..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 32570 MW; F13BCF3E279B1BE7 CRC64;
MTNINARSVT NLSAIPKEEY LYKCTSACAG CSSSLCLRYV LKAAGPDSVL VVPACCTSVI
QGIYPATAMN VPVYNVAFAA AAACASGMSE AFAAMGRETN VIVYAGDGGT VDIGIQALSG
AFERGTNFLY ICYDNEAYGN TGMQRSGSTP LGARTTTTPG GKPTTKKDLD RIVEAHNPPY
MATACSAYPL DLYKKVEKAL SIEGPKFIHI LAPCPPGWRY PTEKTVEMGK LAVKTGTWIL
YEREFGKLSI SGPSKAAMKR PAPLEDYIGG QGRFKNLSPE TLDLMRQQVQ QSIQRLSREE
AGVC
//
