ID A3DPM1_STAMF Unreviewed; 468 AA.
AC A3DPM1;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Peptidase U62, modulator of DNA gyrase {ECO:0000313|EMBL:ABN70581.1};
GN OrderedLocusNames=Smar_1492 {ECO:0000313|EMBL:ABN70581.1};
OS Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Staphylothermus.
OX NCBI_TaxID=399550 {ECO:0000313|EMBL:ABN70581.1, ECO:0000313|Proteomes:UP000000254};
RN [1] {ECO:0000313|Proteomes:UP000000254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43588 / DSM 3639 / JCM 9404 / F1
RC {ECO:0000313|Proteomes:UP000000254};
RX PubMed=19341479; DOI=10.1186/1471-2164-10-145;
RA Anderson I.J., Dharmarajan L., Rodriguez J., Hooper S., Porat I.,
RA Ulrich L.E., Elkins J.G., Mavromatis K., Sun H., Land M., Lapidus A.,
RA Lucas S., Barry K., Huber H., Zhulin I.B., Whitman W.B., Mukhopadhyay B.,
RA Woese C., Bristow J., Kyrpides N.;
RT "The complete genome sequence of Staphylothermus marinus reveals
RT differences in sulfur metabolism among heterotrophic Crenarchaeota.";
RL BMC Genomics 10:145-145(2009).
RN [2] {ECO:0000313|EMBL:ABN70581.1, ECO:0000313|Proteomes:UP000000254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43588 / DSM 3639 / JCM 9404 / F1
RC {ECO:0000313|Proteomes:UP000000254};
RX PubMed=21304655; DOI=10.4056/sigs.30527;
RA Anderson I.J., Sun H., Lapidus A., Copeland A., Glavina Del Rio T.,
RA Tice H., Dalin E., Lucas S., Barry K., Land M., Richardson P., Huber H.,
RA Kyrpides N.C.;
RT "Complete genome sequence of Staphylothermus marinus Stetter and Fiala 1986
RT type strain F1.";
RL Stand. Genomic Sci. 1:183-188(2009).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP000575; ABN70581.1; -; Genomic_DNA.
DR RefSeq; WP_011839775.1; NC_009033.1.
DR AlphaFoldDB; A3DPM1; -.
DR STRING; 399550.Smar_1492; -.
DR GeneID; 4907898; -.
DR KEGG; smr:Smar_1492; -.
DR eggNOG; arCOG00321; Archaea.
DR HOGENOM; CLU_026425_1_2_2; -.
DR OrthoDB; 98233at2157; -.
DR Proteomes; UP000000254; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR025502; TldD.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF0; METALLOPROTEASE SLR0863; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR PIRSF; PIRSF004919; TldD; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000000254}.
FT DOMAIN 23..87
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 118..221
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 230..466
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 468 AA; 51131 MW; ABD79E94AAEE2C73 CRC64;
MNLSSLDLAR LIRYGEELGA EYVDVRVHEK VYELITLDNG VLREYSVNRL RGVGVRVIVD
GFMGYAATNV FDWEEIKKTV VEAVKNAKAL SLHGSKTKLY SRPSYKDKII SHYAVDALEI
DPVEKIEVLK SIYDISKNVR GVVSVIPRYG YEVDHRIIAS SNGDYVDVTT RLIGVGAFIV
SMVEGVSERL WDSRSNVAGW EFIKNMNIEE FASENAKLVV EAAKAPVVKP GKYVAILDNE
IVGLMLHEAF GHATEGDIVE SGGSVLENRI GEKVASEYVT IVDDGRIAGG YYVPYDDEGT
AKKKVKTVEK GVLKTFLHSL STAEKLGEEP TGNARAMTYA HPHLVRQTNT YMEPGDWKVD
ELFKDTRKGI YVRGKGAMGG EVDPAMGTFT FTAGPSYLIE NGEPTKLVRG VMLSGFILET
LKNVDAVAND LVVRTSVFGG CGKAGQLARV GDGGPHVRVR EITIGGGG
//
