ID A3EY52_CAPHI Unreviewed; 526 AA.
AC A3EY52;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Butyrophilin subfamily 1 member A1 {ECO:0000313|EMBL:ABN50060.1, ECO:0000313|Ensembl:ENSCHIP00000025694.1};
GN Name=BTN1A1 {ECO:0000313|EMBL:ABN50060.1,
GN ECO:0000313|Ensembl:ENSCHIP00000025694.1};
OS Capra hircus (Goat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Caprinae; Capra.
OX NCBI_TaxID=9925 {ECO:0000313|EMBL:ABN50060.1};
RN [1] {ECO:0000313|EMBL:ABN50060.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mammary gland {ECO:0000313|EMBL:ABN50060.1};
RA Zhang L., Wu H., Luo J.;
RT "Screening, cloning, and sequence analyzing of gBTN1A1 gene in mammary
RT gland at two lactation stages of Xinong Saanen goat.";
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCHIP00000025694.1, ECO:0000313|Proteomes:UP000291000}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Bickhart D.M., Koren S., Rosen B., Hastie A., Liachko I., Sullivan S.T.,
RA Burton J., Sayre B.L., Huson H.J., Lee J., Lam E., Kelley C.M.,
RA Hutchison J.L., Zhou Y., Sun J., Crisa A., Schwartz J.C., Hammond J.A.,
RA Schroeder S.G., Liu G.E., Dunham M., Shendure J., Sonstegard T.S.,
RA Phillippy A.M., Van Tassell C.P., Smith T.P.;
RT "Polished mammalian reference genomes with single-molecule sequencing and
RT chromosome conformation capture applied to the Capra hircus genome.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCHIP00000025694.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; LWLT01000028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; EF102891; ABN50060.1; -; mRNA.
DR RefSeq; NP_001272547.1; NM_001285618.1.
DR RefSeq; XP_013829487.1; XM_013974033.2.
DR RefSeq; XP_013829488.1; XM_013974034.2.
DR STRING; 9925.ENSCHIP00000025694; -.
DR Ensembl; ENSCHIT00000033556.1; ENSCHIP00000025694.1; ENSCHIG00000022347.1.
DR GeneID; 100860762; -.
DR KEGG; chx:100860762; -.
DR CTD; 696; -.
DR GeneTree; ENSGT00940000161530; -.
DR OMA; AHMELRW; -.
DR OrthoDB; 2943983at2759; -.
DR Proteomes; UP000291000; Chromosome 23.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd15819; SPRY_PRY_BTN1_2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR037958; SPRY/PRY_BTN1/2.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000291000};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..526
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040661038"
FT TRANSMEM 246..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..124
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 148..234
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 285..479
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 526 AA; 59266 MW; BCFADB1E7E63A041 CRC64;
MAVFPNSCLL GCLLIFIALQ LPKLDSAPFD VIGPPEPILA MLGEDAELPC RLSPNVSAKG
MELRWFREKV SPAVFVSREG REQEGEEMAE YRGRVSLVED HIAEGSVAVR IQDVKASDDG
EYRCFFRQDE NYEEAIVHLK VAALGSDPHI NMKVQESGEI LLECTSVGWH PEPQVQWRTH
EGEEFPSMSE SRTPDEEGLF TVRASVIIRD TSMKNVSCCI RNLLLGQEKE VEISIPASFF
PRLTPWMVAV AVILVVLGLL TIGSIFFTWR LYKERSRQRR NEFSSKEKLL EELKWKKATL
HAVDVTLDPD TAHPHLFLYE DSKSVRLEDS RQKLPEKPER FDSWPCVMGR EAFTSGRHYW
EVEVGDRTDW AIGVCRENVM KKGFDPMTPE NGFWAVELYG NGYWALTPLR TPLPLAGPPR
RVGVFLDYES GDIFFYNMTD GSHIYTFSKA SFSGPLRPFF CLWSCGKKPL TICPITDGLE
GVMVVADAKD ISKEIPLSPM GEDSASGDIE TLHSKLIPLQ PSQGVP
//
