ID   A3F6G9_STAAU            Unreviewed;       520 AA.
AC   A3F6G9;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   24-JAN-2024, entry version 49.
DE   SubName: Full=Clumping factor A {ECO:0000313|EMBL:ABN11209.1};
DE   Flags: Fragment;
GN   Name=clfA {ECO:0000313|EMBL:ABN11209.1};
OS   Staphylococcus aureus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1280 {ECO:0000313|EMBL:ABN11209.1};
RN   [1] {ECO:0000313|EMBL:ABN11209.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=67-0 {ECO:0000313|EMBL:ABN11209.1};
RA   Prater B.D., Page H., Liu Y., Gorovits E.L., Syribeys P.J., Lin K.W.M.,
RA   Brignola P.S., Wang J., Hutchins J.T., Patti J.M., Vernachio J.H.;
RT   "Identification and Characterization of Amino Acid Sequence Variants in the
RT   fibrinogen Binding Domain of clumping factor A from Staphylococcus
RT   aureus.";
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC       {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC       {ECO:0000256|ARBA:ARBA00004168}.
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DR   EMBL; EF207780; ABN11209.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3F6G9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1280; -; 1.
DR   Gene3D; 2.60.40.1290; -; 1.
DR   InterPro; IPR011266; Adhesin_Fg-bd_dom_2.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   InterPro; IPR011252; Fibrogen-bd_dom1.
DR   InterPro; IPR041171; SDR_Ig.
DR   NCBIfam; NF033609; MSCRAMM_ClfA; 1.
DR   Pfam; PF17961; Big_8; 1.
DR   Pfam; PF10425; SdrG_C_C; 1.
DR   SUPFAM; SSF49401; Bacterial adhesins; 2.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          211..310
FT                   /note="SDR-like Ig"
FT                   /evidence="ECO:0000259|Pfam:PF17961"
FT   DOMAIN          336..486
FT                   /note="Fibrinogen-binding"
FT                   /evidence="ECO:0000259|Pfam:PF10425"
FT   REGION          1..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          490..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABN11209.1"
FT   NON_TER         520
FT                   /evidence="ECO:0000313|EMBL:ABN11209.1"
SQ   SEQUENCE   520 AA;  55389 MW;  EA380E6BC83456DF CRC64;
     SENSVTQSDS ASNESKSNDS SSINAAPKTD NTNVSDTKTT SNTNNGETSV AQNPAQQETT
     QSASTNATTE ETPVTGETTT TATNQANTPA TTQSSNTNAE ELVNQTSNET TSNDTNTVSS
     VNSPQNSTNA ENVSTTQDTS TEATPSNNES APQSTDASNK DVVNQAVNTS APRMRAFSLA
     AVAADAPAAG TDITNQLTDV KVTIDSGTTV YPHQAGYVKL NYGFSVPNSA VKGDTFKITV
     PKELNLNGVT STAKVPPIMA GDQVLANGVI DSDGNVIYTF TDYVDNKENV TANITMPAYI
     DPENVTKTGN VTLTTGIGTN TASKTVLIDY EKYGQFHNLS IKGTIDQIDK TNNTYRQTIY
     VNPSGDNVVL PALTGNLIPN TKSNALIDAK NTDIKVYRVD NANDLSESYY VNPSDFEDVT
     NQVRISFPNA NQYKVEFPTD DDQITTPYIV VVNGHIDPAS TGDLALRSTF YGYDSNFIWR
     SMSWDNEVAF NNGSGSGDGI DKPVVPEQPD EPGEIEPIPE
//