ID A3FQ19_CRYPI Unreviewed; 3868 AA.
AC A3FQ19;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 2.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=UBA domain-containing protein {ECO:0000259|PROSITE:PS50030};
GN ORFNames=cgd3_1180 {ECO:0000313|EMBL:EAZ51427.1};
OS Cryptosporidium parvum (strain Iowa II).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX NCBI_TaxID=353152 {ECO:0000313|EMBL:EAZ51427.1, ECO:0000313|Proteomes:UP000006726};
RN [1] {ECO:0000313|EMBL:EAZ51427.1, ECO:0000313|Proteomes:UP000006726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Iowa II {ECO:0000313|Proteomes:UP000006726};
RX PubMed=15044751; DOI=10.1126/science.1094786;
RA Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA Anantharaman V., Aravind L., Kapur V.;
RT "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL Science 304:441-445(2004).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAZ51427.1}.
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DR EMBL; AAEE01000004; EAZ51427.1; -; Genomic_DNA.
DR RefSeq; XP_001388099.1; XM_001388062.1.
DR STRING; 353152.A3FQ19; -.
DR EnsemblProtists; EAZ51427; EAZ51427; cgd3_1180.
DR GeneID; 3373941; -.
DR KEGG; cpv:cgd3_1180; -.
DR InParanoid; A3FQ19; -.
DR OrthoDB; 164548at2759; -.
DR Proteomes; UP000006726; Chromosome 3.
DR InterPro; IPR010314; E3_Ub_ligase_DUF913.
DR InterPro; IPR015940; UBA.
DR Pfam; PF06025; DUF913; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006726}.
FT DOMAIN 1679..1723
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 1185..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1640..1664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1957..1977
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2021..2057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2353..2388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2906..3072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3093..3121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3142..3191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3237..3329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3525..3552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3587..3618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3667..3689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3777..3835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2025..2057
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2365..2388
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2907..2977
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2984..3050
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3142..3159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3172..3191
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3237..3283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3284..3298
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3777..3794
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3795..3814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT UNSURE 2943
FT /note="D or N"
FT /evidence="ECO:0000313|EMBL:EAZ51427.1"
FT UNSURE 3182
FT /note="D or N"
FT /evidence="ECO:0000313|EMBL:EAZ51427.1"
SQ SEQUENCE 3868 AA; 442791 MW; DF415DF8B56A022F CRC64;
MKISIPKGDN YILAVSSLPQ SQRELILKLS SDDVTNYDSY LDSFQRWIWD KGDLQCWASV
LNRFDDYINS YIIREELGNP FLLQHLTLTD ESTELSHSNE NILKQANGYI RDVSEEMMKK
ILKSTFLILE NCTSKSLYAS TIGLIALLDS SNPDIVCWSL RTLTTTCSNW KKPKRYIDSE
TVYHLQMRLS TLCYLPIHTR SSNKSGIENK ENEALSSLTS FYKEETWKNP DDDDLIEVYI
PPFICNHFIR KDSDSEEKEC KMCFDYHKSH ILMIQFKDLI SVNSKPEVDD LMRKYKVPIC
LKSIVNHYVR ILKSYSDKWL RRKWVDVKYT TLLSFPGFST NNLVNICQVN TTLIPDSIEI
LEFCHLSIFE GNSKVKLNNN NEQYRFITSM RSIVELLTLM LQDRIFPKVI VQALNFTNSY
GLISRIIWDI LYYINDHKDR PLPKFIKKPP ESLNQYKYND QNLSNNLLDF EGDYSQFNIL
EYIDPSIFNN VNYPLPDQVI QRLSEIQINY DKIEENNGNE DGENCYYKGN KLDNQTSVEL
HKKYNTSLSS YMDLESAKDE ILLINNYYEN LDLEFQKKTI NDSSKIIPNL IMAEFEEEMI
NFVMELIGIY ILVMQLYPPP NSIVTNSSSS STSYIYIPHH ITILIAFIDF ISTIRHPYYI
ILVLPICRAL ETLLEKKTYI SFLLQQNKPI YKIMLSRLQY EIGLLQSEKY YFDSPKEEYK
NKIIKDEGVI LIRQWIIKTS LKFMELFIHP NNNSLVSNSD SNPIISQSKI QYELLMSEDS
IYRSCLMLIL MYPETYSLLN YSLVIQLLIP LVSNDPTIVP DLINNHLIPF ILYSINFGIL
QNDDILNILA VNLPIFFLHN DGIKLMKSIN FKPLILLSQF LTSSHAIHID RMGEIATLVG
NAFEEIVRYH SQLAKTISLI SVSAILQIRF IQKCLPKWEP ISEISKESLD SPEEYYTPIK
IPKKSKDLLI SDRMAIVGRF LCGYLSNHDT INQFILQGGP YHVLRSIVDD SLPPAFAAIL
TNHPLISLFT FLGTSRNISI ADLQYQVLPT LQEACKDFKN VEVDHNSISR LSKVVTCIFA
INCMFRNAAN YNHSRIVQSY LISKDIVKLQ DSTSPCDYCP YGASIMSLYN QAVNMIAPIF
PKLLEFLYFN ASEKYLQDSL LSNNNMSASL LNPSFQSHAH PLLIKKDNSS NNQPTNTQNN
SSGINNAQES PTCSTSYPVL SVWPQLSVND FLWSTQIKYA YSNVVYYEQN SENLSEISKD
TDLMPIIMEL CRISCCNIRS CLILASRLTN TFKKKNNASL LFRNDXGXPX XLXXXISXXX
XXXFSNCRPF LXXFXNLFQN CPXHLKILII PVLRXLXTLC MSFPLLHAMN TRKHEMGQIC
CYIAEIIDVF YRVCIDDKQN NTFYIFLIDL SYKTGIFEKI MSLFHFSMST YWMVLGKXIG
KHNTENVNKM LPPLNPSSRL KYSSEFLGQL SEYILPKLSS VHNLNGLLYL ATKSMHNNIL
LLEHFSSWKR YLNSTXTTHL HKSKFHLNNC XPIISNTNSA ELNIFDSSLD SFFRMEFNSV
ELTESILLMI ITNIQLWWKE VLTNYYLDMA HNNWLIFYPI RCLSSTFKIM LHIFDIQSDS
FNSFVAKNFD QSNDKTVKXN SISDADARSS SSTSNDNLQX SSNLNIDSSV QNHDASLTXQ
DENTVNSILE RLNMMGFDSR VSEHAIFCFG NNIEVIVEYL TGVTERNENK TMISEEAGNY
MYSFRRIGKV LSEQFELGKL IXYKTLSKED KKSEILRXYS TLPSELYYLS KNVYYSSPIV
CDIMLKFSPL LKKINMLEKV LFHIYTSMKM LLERNQSVFS XESSNHRYQF IKEELSFLQD
EXLNNDKFPI IFNSFYTSLN NSTPLIDSNS NFNKLNYQEI YSNLDXYSKK CAPTKKIHLS
LIPDLSLLSI LLYKKTDLKS FWISIDSNYI KLTSTQNKNS SKSKNKSNIS NSNTEQVPEQ
SFHPINSLLS FVNIFTQGHY IFDSXHDGFT FKNMEKYIRD NLGEGNGQXT GQNNQNGNNI
NSNSNSNNMK SXQRPSSLVW IPANKETESK EYNDKGIKLA SRCPIWFEYF CLILWRLLPI
FEQSIPVSES SNTPFLVSQK NQKDIIFTML DILTHFPGIN GSTSMAVLGV ITILTRXFNN
SLLLLSYTPF YMIEMHKNKD KTQNIACMCM GNTLGGGLGV LYRLPKTAYF DGILQVLSLI
TIQVLEDFTI LTQLIENKLD ELFSKQLSTQ IQSGEIYGEN LQVVNXTENN TENQENENPN
SCKYFSFYPR SFTLNYKKDL KLLEKKEIEY PFIVLSLNSV IGELFPYIQR CPEIFYQVLN
YFCVLHSIKT GNESSSNSKX NSEDHCSDXN YKAKSEPXEN DDVLMNDENK XKDDSAFTXI
KYTTFNDLME NQEIYSKYNI PVNENLLLQW KPLNYRNSEA TQEEQNKYLE LKEKLKYVQG
DSALRPSSTC MFILMSIFDH MVLFGEIXNK SKFGKKRGIN SCLRGRKDDE IFSLSLDSLT
YIMIRIALTY PVNINRISKV PILSICNENN ARLWQEKKRE FYSYRYRNSS NLKLGVSCFC
LNLQKSLSTI DSENKKELKA ALEQEFSGIS TVIPNIHSLT NNIIKFKPYS FEFLLNQLFV
TQSLKINFLP FIFRNIASYI VMNSINCMTS MPTCTCKKCK QAGSPSSGTE ENSPLKMAGW
QLNLDWQTYN LKCMPNLSTI KKSNIKDVHF MEMDHFIYFL HILIGWNKFV LKKFMVYTVN
SLRNLLASLD KFKGNSNRHN WRSEYVNSYF LLNILQYLIV LLQVYPSISD PGLLRKASIY
NILSKLYVKL PYSDLSNIIL FCMKNLIYSR SVMMPNSEXL AAIKEGSLDS KVKKVRNSIG
VGNGNDQLXD DQLEVDLDQF GFQFNSSDED FDDDLDDSLE DDFSEEFDLT SLDGLDXEDI
DDDDEDDDDN DVEDMDDDXE DDVEDDEDDE XDDLFLDETM INDGVIDIEG EDDDLSNDDI
VGDDDLTSDV DDVDDDDDDD DDDDDDDDDD DDDDXDDDDE GDDEDGMNFD ESDMXSGMSS
EDSDVDELRR TPRIRDEYEF NYIYQMNNQT NINGLEDVPM NTSSEEVEED GGENINEILM
RDAERNGQNR IILNNLRXSA FRRNTSTGGG SSSSRRRSGR GYNRSIRDDL DNDLNFDDDE
DDDLDIDDLD DEIFGEEYNS EEDNEDINIL QGINNIVTNT NITPTLLISD GVNNTVVQGT
ENSNVTGSAN XNSNSDNNIN NNNNNNNNNN SSSIEQXSEL EQALPEQRNE REATEESEAX
XENSNNGAGY SXLRTPPHPL RREELISNTT IRNSNQLNEV NENILGNEVS PAPLRRRIAS
QGNNYLDDMM MVLLREDDDD FEIDNLQFLE DLSSLGGVXG SAGLSLGGEG GRDDLQVQFL
GTQGVGTGLL NNLIPNTNNT VYNESLNSSF YLDSTEAHWP PMPLNQRNIF INSRNIPLXF
LILNSLTFVP NTSNLNPPSN NDLILQWMSY GGYLTNPVLS HYNIGNVRNX DSSGNSXGGS
NNXNSFSINN STNNNSQPAF GWHFHNDISL PTEHPFLTRN IIIDNNMGIN SSGNSNNHGS
GSGNNNSNSH TNNLSWYSNG PLYDSQRSLI GEIHSSSLRN NSELSILMDA IRNADNLTNN
DDXITXMQNN SNNGNGITNT CTEGGATSTN XNLGGXSSLR GSNLNVSTLI RNIGDINRNN
NLDRLLTDEN NSTVSLIPLV LVSQATSFLR DAVSSKIPIE TNNINLFTTN IEQDEESDNH
TFDLQERGDV ICDNQLDDNT ENMDSIQGGE EXXQHQDQEQ SDDDNEDDEX XXDSXXIMMM
TALMMKMVKK LTKKAMKTWR MKDYWIAK
//
