ID A3GF39_PICST Unreviewed; 427 AA.
AC A3GF39;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 16-JUN-2009, sequence version 2.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase) {ECO:0000313|EMBL:EAZ63280.2};
DE EC=2.6.1.62 {ECO:0000313|EMBL:EAZ63280.2};
GN Name=BIO3 {ECO:0000313|EMBL:EAZ63280.2};
GN ORFNames=PICST_38592 {ECO:0000313|EMBL:EAZ63280.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:EAZ63280.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:EAZ63280.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Cofactor biosynthesis; biotin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004746}.
CC -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|RuleBase:RU003560}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAZ63280.2}.
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DR EMBL; AAVQ01000001; EAZ63280.2; -; Genomic_DNA.
DR RefSeq; XP_001387303.2; XM_001387266.1.
DR AlphaFoldDB; A3GF39; -.
DR STRING; 322104.A3GF39; -.
DR GeneID; 4850888; -.
DR KEGG; pic:PICST_38592; -.
DR eggNOG; KOG1401; Eukaryota.
DR HOGENOM; CLU_016922_4_3_1; -.
DR InParanoid; A3GF39; -.
DR OMA; LLGGFTH; -.
DR OrthoDB; 5487177at2759; -.
DR UniPathway; UPA00078; -.
DR Proteomes; UP000002258; Chromosome 1.
DR GO; GO:0004015; F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00610; OAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR HAMAP; MF_00834; BioA; 1.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR005815; BioA.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR00508; bioA; 1.
DR PANTHER; PTHR42684; ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR42684:SF21; ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE; 1.
DR Pfam; PF00202; Aminotran_3; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000256|ARBA:ARBA00022576,
KW ECO:0000313|EMBL:EAZ63280.2};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|RuleBase:RU003560};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EAZ63280.2}.
SQ SEQUENCE 427 AA; 47034 MW; 84ABD9BB9763F8C6 CRC64;
MKGLRQKLLY DSRHIWHPYT SMISPLPCYH VKSASGVSLQ LSSGETLIDG MASWWSAIHG
YNHPHLNKAA HNQIDKMSHV MFGGITHDPA IDLCKQLLDM TDSNLTKVFL ADSGSVAVEV
ALKMAMQYWH SKGEKQRKRF LTIKHGYHGD TFGAMGICDP VNSMHSIYTG YLPQNLFAEA
PHIRFGEQWD EKDISSFKAI LERNSKEIAA VVIEPILQGA GGMRMYHPQY LKSVSELCKQ
HGVLLILDEI ATGFGRTGRL FAYEHAGICP DILCLGKALT GGYLTMSAVL TNDDVAETVS
SGESGCFMHG PTFMANPLAA AIASASLELV NEGNWKTQVK SIEDVLKLGL NPLSDHPKVQ
DVRILGGVGV IEMKNPVDMA RCQKALIQSG VWLRPFGKLI YTIPPYIVSK SELLKIIDTM
GILVDIN
//
