ID   A3GHF4_PICST            Unreviewed;       804 AA.
AC   A3GHF4;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   16-JUN-2009, sequence version 2.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
DE   Flags: Fragment;
GN   ORFNames=PICST_53894 {ECO:0000313|EMBL:EAZ63046.2};
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104 {ECO:0000313|EMBL:EAZ63046.2, ECO:0000313|Proteomes:UP000002258};
RN   [1] {ECO:0000313|EMBL:EAZ63046.2, ECO:0000313|Proteomes:UP000002258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC   {ECO:0000313|Proteomes:UP000002258};
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAZ63046.2}.
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DR   EMBL; AAVQ01000002; EAZ63046.2; -; Genomic_DNA.
DR   RefSeq; XP_001387069.2; XM_001387032.1.
DR   AlphaFoldDB; A3GHF4; -.
DR   STRING; 322104.A3GHF4; -.
DR   GeneID; 4851703; -.
DR   KEGG; pic:PICST_53894; -.
DR   eggNOG; KOG2208; Eukaryota.
DR   HOGENOM; CLU_012167_0_0_1; -.
DR   InParanoid; A3GHF4; -.
DR   OMA; LIKCPRK; -.
DR   OrthoDB; 1408909at2759; -.
DR   Proteomes; UP000002258; Chromosome 1.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   PANTHER; PTHR10627:SF69; PROTEIN BICAUDAL C; 1.
DR   PANTHER; PTHR10627; SCP160; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   SMART; SM00322; KH; 2.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002258};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT   DOMAIN          480..562
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   DOMAIN          577..654
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   REGION          781..804
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        790..804
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         804
FT                   /evidence="ECO:0000313|EMBL:EAZ63046.2"
SQ   SEQUENCE   804 AA;  91998 MW;  62F80CFBC0287D3B CRC64;
     MNVSVLNLEY FFAVNPNVST YFESNNGLWR DYISESGASY RMVDNLIPLH DIVNSINLHQ
     IQMKSTSNYI TIMEPKIKNQ LITVSIHGNQ DFIRNSKSEV LSRYSQVNTK TIQISQREFL
     AINEKFTSQL FKLCSQYHTE IVINNSKMTQ EDGIGALSGY YIHVLGSQDN ITITESSLRI
     LIDNILNNYF LDSIDIQLSM IPLIGGIQLF NFNQVAKQSN SNIYIPDLLP SLFNSKIFSN
     TSNVKLWITA KTIPEILLTK NIIDKISEER FRNDIIVKEI ELTKVKIDLM TLYNQSEILN
     IMFKHGIFIQ MPSLGEKNNC KILIQGCSLE AVNEAVLEVN LLSTSYYCVQ LNCVANQLNE
     YNLIQLMQDR KTCVITSNRF GIDINGNSGE IKQLLNDMAA TPCIDFNTLK LRLELHNNQR
     DFISGKKNGK LIKIMNQLNQ LPMIKFSPFN EYNFYIDFEI YEGTNMSVLL KGLDLIEMEL
     PSELKFNIPE VFHKSIIGNG GSIIQSIMKK YNVFIKFSST VSGTTSKNIY SFKRYDNVLI
     KCPRKNSKNI QLVKNEIDQL VYQCCLNNNP PKSFPNATTT VYHTVKFQLL KSHYLLLINN
     NKLQIINELE NENNTYINFP TSIEEFKGND VIVEIKGSEA RTKHCFKQIE AMLPKNYEFK
     VTMSVGKFEE TFSGVNKQDF YNNVIVPFKI LLGVEISVNS TPIARSSSNE NTASSTEDYH
     QIILSYYNEE SLKPAIDSLT LYLRQHGFLI LDKKALEFNP LVETVKPNVM ALRSLSNQAV
     DNQGNKPAYK KHKSPVKQPK VHYN
//