ID A3K8S9_9RHOB Unreviewed; 299 AA.
AC A3K8S9;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Dihydrodipicolinate synthase protein {ECO:0000313|EMBL:EBA06517.1};
GN ORFNames=SSE37_14979 {ECO:0000313|EMBL:EBA06517.1};
OS Sagittula stellata E-37.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Sagittula.
OX NCBI_TaxID=388399 {ECO:0000313|EMBL:EBA06517.1, ECO:0000313|Proteomes:UP000005713};
RN [1] {ECO:0000313|EMBL:EBA06517.1, ECO:0000313|Proteomes:UP000005713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E-37 {ECO:0000313|EMBL:EBA06517.1,
RC ECO:0000313|Proteomes:UP000005713};
RA Moran M.A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EBA06517.1}.
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DR EMBL; AAYA01000015; EBA06517.1; -; Genomic_DNA.
DR RefSeq; WP_005862554.1; NZ_AAYA01000015.1.
DR AlphaFoldDB; A3K8S9; -.
DR eggNOG; COG0329; Bacteria.
DR OrthoDB; 9778880at2; -.
DR Proteomes; UP000005713; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR42849; N-ACETYLNEURAMINATE LYASE; 1.
DR PANTHER; PTHR42849:SF1; N-ACETYLNEURAMINATE LYASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000005713}.
FT ACT_SITE 140
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 164
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 52
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 299 AA; 31594 MW; EF31B4EB97D93349 CRC64;
MSSDLHKSLT GVSGILVTPF DEAGEIAPDL QRPIVERAIE AGVHILTANG NTGEFYGLTL
EEAQAMVHAA GQHIDDRVPM VAGVGRGIRD AQALAEASGL AGASALMIHQ PPDPFVSPRG
LVRYVEAVRE AGDGLPIVLY LRNDTIGTEA IRAMCLVEGV IGVKWATPNP MKLKAAIAAC
PDDIVWTGGL AEVWAPTFYA VGARGFTSGL INVWPERSVA INTALENGDY EEARALIAGM
QVFEDIRAEE QGGANVPGVK GALQMMGEDC GAARPPAAWP LSDSQRLRLE TFMTTNGLI
//
