ID A3LSP4_PICST Unreviewed; 293 AA.
AC A3LSP4;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Degradation of aromatic compounds {ECO:0000313|EMBL:ABN65932.1};
DE EC=5.3.3.10 {ECO:0000313|EMBL:ABN65932.1};
GN Name=UMH1 {ECO:0000313|EMBL:ABN65932.1};
GN ORFNames=PICST_58067 {ECO:0000313|EMBL:ABN65932.1};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN65932.1, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN65932.1, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR EMBL; CP000497; ABN65932.1; -; Genomic_DNA.
DR RefSeq; XP_001383961.1; XM_001383924.1.
DR AlphaFoldDB; A3LSP4; -.
DR STRING; 322104.A3LSP4; -.
DR GeneID; 4838347; -.
DR KEGG; pic:PICST_58067; -.
DR eggNOG; KOG1535; Eukaryota.
DR HOGENOM; CLU_028458_2_1_1; -.
DR InParanoid; A3LSP4; -.
DR OMA; PASECDW; -.
DR OrthoDB; 9433at2759; -.
DR Proteomes; UP000002258; Chromosome 3.
DR GO; GO:0008704; F:5-carboxymethyl-2-hydroxymuconate delta-isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF100; FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G01490); 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:ABN65932.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258}.
FT DOMAIN 80..290
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 293 AA; 31996 MW; 49D2EA813AFA4CFE CRC64;
MTPTWKRLIR FVAQDGKTYR GEPIVSDADY DVGKQFLQGK QIMAKVITGD IFDNAVVTDV
IKEVKTLLGP LTPDDVPMVK CVGLNFMKHI QEGGRTPPPF PSIFYKTSFS VADFGEDIPI
PKIAQSKCDY EGELCIVIGK TGKNIKEEEA LSYVAGYVTG NDVSSRNWQK DPEFAGSVPQ
WCFSKSFDKY APLGPALVSP QVIQNPGNLS LQTTVNGEIR QDANTDDLLF GVPRIISFIS
QSTTLEMGTV IMTGTPSGVA LGMKPTPVYL QNGDVVEVAI DQIGTLSNKM VFE
//
