ID A3LSR5_PICST Unreviewed; 362 AA.
AC A3LSR5;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2007, sequence version 2.
DT 24-JAN-2024, entry version 79.
DE SubName: Full=D-threo-aldose 1-dehydrogenase {ECO:0000313|EMBL:ABN66280.2};
DE EC=1.1.1.122 {ECO:0000313|EMBL:ABN66280.2};
GN Name=YMT1 {ECO:0000313|EMBL:ABN66280.2};
GN ORFNames=PICST_58212 {ECO:0000313|EMBL:ABN66280.2};
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN66280.2, ECO:0000313|Proteomes:UP000002258};
RN [1] {ECO:0000313|EMBL:ABN66280.2, ECO:0000313|Proteomes:UP000002258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC {ECO:0000313|Proteomes:UP000002258};
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- SIMILARITY: Belongs to the aldo/keto reductase family.
CC {ECO:0000256|ARBA:ARBA00007905}.
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DR EMBL; CP000498; ABN66280.2; -; Genomic_DNA.
DR RefSeq; XP_001384309.2; XM_001384272.1.
DR AlphaFoldDB; A3LSR5; -.
DR STRING; 322104.A3LSR5; -.
DR GeneID; 4838365; -.
DR KEGG; pic:PICST_58212; -.
DR eggNOG; KOG1576; Eukaryota.
DR HOGENOM; CLU_023205_7_2_1; -.
DR InParanoid; A3LSR5; -.
DR OMA; AVQSYAN; -.
DR OrthoDB; 1581031at2759; -.
DR Proteomes; UP000002258; Chromosome 4.
DR GO; GO:0047834; F:D-threo-aldose 1-dehydrogenase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR InterPro; IPR020471; AKR.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR42686:SF1; ALDO_KET_RED DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR42686; GH17980P-RELATED; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ABN66280.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000002258}.
FT DOMAIN 32..318
FT /note="NADP-dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00248"
SQ SEQUENCE 362 AA; 41057 MW; 3419F0AB5C8888E1 CRC64;
MPEFLEPQTN ESQAIGDSIV VQPYSIANLP PLVVGGAVFN TQYSSNPSSL PIQEILEDAF
AKGLNAIDTS PYYGPSEILL GEALKKISFP RQEYYICTKA GRVKLDDFDY SRDSVRKSVE
RSLERLNTSY LDLVYMHDIE FVKEDEIFDA LKELKLLKTE GLIKNFGISG YPVRFLHKIA
SRSVGIPEIG PLDAVLSYSN GCIQNTRLFE FYDQFFDDCK LKKLSNGSIL SMSLLRSDIT
HSFHPASKEL KDKVYDIAHL LKKEYNGLEL ADLATRFALR KWLFETVHQA DSSNLHWNPS
TSIVLGVSNV EELDVAIRCY WQVKNNIDNI NTKDDILFEK VKNLLGPEHF NEVWPSGIDG
RQ
//
