ID   A3LWT8_PICST            Unreviewed;      1298 AA.
AC   A3LWT8;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2007, sequence version 2.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=Protein STU1 {ECO:0000256|ARBA:ARBA00016012};
GN   ORFNames=PICST_78610 {ECO:0000313|EMBL:ABN67335.2};
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104 {ECO:0000313|EMBL:ABN67335.2, ECO:0000313|Proteomes:UP000002258};
RN   [1] {ECO:0000313|EMBL:ABN67335.2, ECO:0000313|Proteomes:UP000002258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545
RC   {ECO:0000313|Proteomes:UP000002258};
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC       {ECO:0000256|ARBA:ARBA00004186}.
CC   -!- SIMILARITY: Belongs to the CLASP family.
CC       {ECO:0000256|ARBA:ARBA00009549}.
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DR   EMBL; CP000500; ABN67335.2; -; Genomic_DNA.
DR   RefSeq; XP_001385364.2; XM_001385327.1.
DR   STRING; 322104.A3LWT8; -.
DR   GeneID; 4840111; -.
DR   KEGG; pic:PICST_78610; -.
DR   eggNOG; ENOG502QT5T; Eukaryota.
DR   HOGENOM; CLU_261691_0_0_1; -.
DR   InParanoid; A3LWT8; -.
DR   OMA; AKECYWC; -.
DR   OrthoDB; 1369289at2759; -.
DR   Proteomes; UP000002258; Chromosome 6.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:UniProt.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024395; CLASP_N_dom.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR21567; CLASP; 1.
DR   PANTHER; PTHR21567:SF9; CLIP-ASSOCIATING PROTEIN; 1.
DR   Pfam; PF12348; CLASP_N; 1.
DR   SMART; SM01349; TOG; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00022776};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002258}.
FT   DOMAIN          292..546
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REGION          580..647
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        588..607
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        608..626
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..646
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1298 AA;  147723 MW;  EAA22703E6A3A9F6 CRC64;
     MSSHHKVYAN ELFQIMASRD VDQTRKLELV LKLKTNIKKD AVDIAQVPTY FEALSIGVDI
     PDLGISVASF STLAHLIKRV SMQDKTGMVL KNQSFLVLPI IINRLANSNT STLSSARKAL
     EAYWFSSPRE VESAILDIAL KHRNTDITLE AVHWLHHIIS NVNQHFNLTR FVPQLAKLLA
     TYPSSHSTQL QNSIKSLLCD YYNFKQNRLY KFDLARELEL KNVPDTIKES IMQNIAGINP
     ESTSVTKPDS NFVIAVQDHQ SIPSEAETLL PEIRDIISKY NYELDTSIRS VSFEGSEQML
     STFNDLLPPF NSKETEFNWG QREKNIVQMR SILRGNAPSL YRRDLIVGLK DSAEAICKAV
     SSLRTTLSSH GCQLVKECAI FLKTDIDSLV DLFMPSLVRL CAATKHIAST NANMSIVAIC
     ANASYSPRLL QRIVNATNEK NVQPRSYSGI WLQITVSRFF NSHSFLSSHG STPNTGVDLA
     MKALAKLLKD PNPTVRQIAK DSYWCLWRKL PTQSELLLSK LEPKIIKIVE RSRPKDVSHE
     EVSAPTLNMQ RSRPSLKETI IERNKDLRLK QRELNQSHRE ELHIKRVATR TNSTNGFRQN
     SIERNLSNSH KPDLRPPSKE GVSPKDIEQE SVQQETTRTK QTDTAPASKE VAFDVQADPI
     LKFLSSYQTD LIKEGINLLK YAIMGEEELS PEITSLLKSI SLRQPKLLEP LLLSNDNLFK
     RSFQFFSAED FLRICSIVIN PIEGRTIELL ISMMTVDELY ESIIKLLSYS INTANILGDD
     ELTMQVIKYK SSIIQLIVVF LQSSLEKIPI RDSYFSKVTS NFLELVSILK STDIYPEFSK
     LLAKLYSINI ALFVSELDLV DINTKEEVEY IVGIDHTLSM KNIPNTMPNS LFELTEVQKT
     HSYDGFSPVK TNQDFTMIWP ERKDNDDYNF IPKSANDSQK NIAAQFQGFN HHESKSEDPV
     KEYSDNLAQV QICEQPPSLI DQNVQLQTFL DKVDPLKSIS NRNKPIAIYE DSKGSPQKLK
     EHRYSEFNWF NFQVARLQLE SDDDEVEDNE TTEDDYSELL MDVCESLKSL ELDSKTLTTA
     LDLLQNMHRF GFEFVKYYEN EGAKLMEESL WQFFHDCNKV SITNKVRGLV LLKQLLIIHS
     KLDLANLWTT LINVACLPDS ENEIAFALRD ISSEILSGLY RSDELLDVLF SSFTSDHLSR
     ASTFILGTLS KVLDSTSIPE LLSDSILQQI DRVLRNFVNS RNAECRRYAI LCYGKLVKSS
     RVSFAGKSPD NTILDGIIQR FSPSQRRLVE YYSQDPKS
//