ID A3RI36_LISMN Unreviewed; 1073 AA.
AC A3RI36;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=IspD {ECO:0000313|EMBL:ABN80103.1};
GN Name=ispD {ECO:0000313|EMBL:ABN80103.1};
OS Listeria monocytogenes.
OC Bacteria; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=1639 {ECO:0000313|EMBL:ABN80103.1};
RN [1] {ECO:0000313|EMBL:ABN80103.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LI0521 {ECO:0000313|EMBL:ABN80103.1};
RX PubMed=17577052; DOI=10.1099/jmm.0.46977-0;
RA Yu W.L., Dan H., Lin M.;
RT "Novel protein targets of the humoral immune response to Listeria
RT monocytogenes infection in rabbits.";
RL J. Med. Microbiol. 56:888-895(2007).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the internalin family.
CC {ECO:0000256|ARBA:ARBA00009432}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EF409983; ABN80103.1; -; Genomic_DNA.
DR AlphaFoldDB; A3RI36; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.1220; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR Gene3D; 2.60.40.4270; Listeria-Bacteroides repeat domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR014755; Cu-Rt/internalin_Ig-like.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR012569; Inl_IR.
DR InterPro; IPR013378; InlB-like_B-rpt.
DR InterPro; IPR044056; InlI_Ig-like.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR042229; Listeria/Bacterioides_rpt_sf.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR032675; LRR_dom_sf.
DR NCBIfam; NF033932; LapB_rpt_80; 5.
DR NCBIfam; TIGR02543; List_Bact_rpt; 1.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF3; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 ISOFORM X1; 1.
DR Pfam; PF09479; Flg_new; 1.
DR Pfam; PF18981; InlK_D3; 4.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF08191; LRR_adjacent; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR PROSITE; PS51450; LRR; 2.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1048..1067
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1040..1073
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 1004..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1015..1040
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1073 AA; 115724 MW; 7EAD8C0878BF2B27 CRC64;
MKSKTKQIIM IGVVLFQSLF AYPLITMAEE NESKSVNTET TLEPKVALEE KTPQKPTLTN
NLKQEKTVLQ AGETYETVFP DAALATVIAK AATGSEDITQ EVSQTDLNKI TSLAATSKGI
VDLTGIDLLS KLTSLSISGN QITDISALNG LVNLSNLNVS NNKITSFNLN ANSNLPMLSA
VDIRSNNLKN RNVQDQPKLR TIECDTGSSS ELTEVTLKNL PTLIVAGNGS SAYQNDIVFS
STPGLSKVIL ENLPSISSSV RLDRCAIEEL VINNLPKKSM VNISNNKITT LEGLENLSAV
NTLYVSENLV TEIESMHAFP KLQNLELGWN ALTNVVMDQV TAEKLPLLRT MDVRGNNLIK
INIQDQPKLW TFECDTGSSS ELTEVTLKNL PILIVAGNGS SAYQNDIVFS STPGLSKVIL
ENLPSISSSV RLDRCAIEEL VINNLPKVSM VHISYNKITT LEGLENLSAV STLYTYENLV
TEIENLHAFP KLQTLTVDYN ALTVVPTDLK TENPVLTTLS AMNQTITLKQ KVIVSDLVLD
NEVKNFGQIT TAKSISNKGT YQNNQIKWLF EDIKSVNAVD YQFSEPVQEA TIQGTFSGKV
TQPIKASKVP VISADAEMNY PKNETVSEAA FFKDISASVT DDATLTSDFE SVVDFAKAGT
YEVTLNAVNE DGVKATSVTV LVHIAKSPAP VITADKEITY TKNAEVSITE YLAAIHAKTN
DGSPIESDFA TAVNWGTAGD YTVTLRSTNE DGVEAIPVEV TVHIAKSPAP VITADKEITY
AKNAEVSITE YLAAIHAKTS DGSSIEADLD TAVTWGTVGG YTVTLRSTNE DGVEAIPVEV
TVHIAKSPAP VITADKEITY AKNAEVSMTE FLAAIHAKTS DGSPIESDFA TAVIWSTAGD
YTVTLKSTNE DGVEAIPVEV KVHIVEPLAP TISNVTFDVD DVQTTESLEA GELISEPLSP
TKEGYTFIGW YDSKTGGNKW DFTTDKMPAY NIILYAQFSK DTNKAEAAGG DKPSTPSSIK
VSPTGQSESG NLENRSNIKL PATGDDNATV LLVGFGLLML GLFIRLTQKK RAK
//
