ID A3SLR1_ROSNI Unreviewed; 306 AA.
AC A3SLR1;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE RecName: Full=HTH-type transcriptional regulator MetR {ECO:0000256|ARBA:ARBA00019365};
GN ORFNames=ISM_08345 {ECO:0000313|EMBL:EAP78292.1};
OS Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=89187 {ECO:0000313|EMBL:EAP78292.1, ECO:0000313|Proteomes:UP000005954};
RN [1] {ECO:0000313|EMBL:EAP78292.1, ECO:0000313|Proteomes:UP000005954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-591 / DSM 15170 / ISM
RC {ECO:0000313|Proteomes:UP000005954};
RA Moran M.A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAP78292.1}.
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DR EMBL; AALY01000001; EAP78292.1; -; Genomic_DNA.
DR RefSeq; WP_009813692.1; NZ_CH724156.1.
DR AlphaFoldDB; A3SLR1; -.
DR STRING; 89187.ISM_08345; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_0_5; -.
DR OrthoDB; 155872at2; -.
DR Proteomes; UP000005954; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd08441; PBP2_MetR; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR037406; MetR_PBP2.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30126; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30126:SF25; HTH-TYPE TRANSCRIPTIONAL REGULATOR METR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methionine biosynthesis {ECO:0000256|ARBA:ARBA00023167};
KW Reference proteome {ECO:0000313|Proteomes:UP000005954};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..60
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 306 AA; 34401 MW; 67B4C89909B6B2F5 CRC64;
MHIEFRHLRT IRAIHQAGGL ARAADLLHIT QSALSHQIKG LEDQAGVELF VRRSKPMKLS
AAGLRLLRVA ERVLPEIEAL EDEFSGLREG SSGRLHIAIE CHACFEWLFP VLEQFRKPWS
EVDVDIRPGL AFDALPALQK EEVDLVVSSD PETLPGISFK PLFDYEPVFL ASRHHPLAEK
PFVVAEDFRD ETLITYPVDR SRLDVFTELL TPAKVEPKAT RQVELTAVIL MLVASGRGVA
VLPDWVVREL HGSSDYVVRR VTEAGLTKRL YAAIRDDDAD KPYMSHFLKL GRDIPVRLQR
RAAAPA
//
