ID A3SR24_ROSNI Unreviewed; 386 AA.
AC A3SR24;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:EAP75047.1};
GN ORFNames=ISM_10685 {ECO:0000313|EMBL:EAP75047.1};
OS Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=89187 {ECO:0000313|EMBL:EAP75047.1, ECO:0000313|Proteomes:UP000005954};
RN [1] {ECO:0000313|EMBL:EAP75047.1, ECO:0000313|Proteomes:UP000005954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-591 / DSM 15170 / ISM
RC {ECO:0000313|Proteomes:UP000005954};
RA Moran M.A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAP75047.1}.
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DR EMBL; AALY01000004; EAP75047.1; -; Genomic_DNA.
DR RefSeq; WP_009814146.1; NZ_CH724156.1.
DR AlphaFoldDB; A3SR24; -.
DR STRING; 89187.ISM_10685; -.
DR eggNOG; COG0626; Bacteria.
DR HOGENOM; CLU_018986_2_2_5; -.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000005954; Unassembled WGS sequence.
DR GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:UniProt.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF93; CYSTATHIONINE GAMMA-LYASE-RELATED; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000005954}.
FT MOD_RES 205
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 386 AA; 42768 MW; D1122258C3E4C0C0 CRC64;
MSDRRNRPLS PSTKLAQALR YLDRETGAIV PPIQPSATYA RDEDYAVRRS YMYRRDGNPT
TEQAEAIIAD LEGAVDCMLF SSGMSACMSV IDTLKPGDHV VVPEVMYHGV LQQFQRYAKL
HRLEVSYYRP GDLDALRDAC RKGKTRLVWV ESPNNPDWDV TDIAAAAELA HAAGAKLLTD
CTGTPPCATR ALELGADFSF HSATKYLNGH SDVTAGALSV RNMDAWWEEI EGHRKLQGTV
LQSFDAFLLI RGMRTLTLRY ERATLNALRI ATHFEGHPQV RKVLYPGLES HPDHDIAKRQ
THGMYGGMMS IIVKGDEQAA IDVARFCQLF YPATSLGGVE SLIEHRKTVS GEGFKVHPAL
LRLSIGIEDA DDLIADLEQA LDRALG
//
