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Database: UniProt
Entry: A3UI32_9RHOB
LinkDB: A3UI32_9RHOB
Original site: A3UI32_9RHOB 
ID   A3UI32_9RHOB            Unreviewed;       478 AA.
AC   A3UI32;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-SEP-2017, entry version 69.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=OA2633_09574 {ECO:0000313|EMBL:EAP89505.1};
OS   Oceanicaulis sp. HTCC2633.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Hyphomonadaceae; Oceanicaulis.
OX   NCBI_TaxID=314254 {ECO:0000313|EMBL:EAP89505.1, ECO:0000313|Proteomes:UP000006011};
RN   [1] {ECO:0000313|EMBL:EAP89505.1, ECO:0000313|Proteomes:UP000006011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2633 {ECO:0000313|EMBL:EAP89505.1,
RC   ECO:0000313|Proteomes:UP000006011};
RX   PubMed=21036991; DOI=10.1128/JB.01267-10;
RA   Oh H.M., Kang I., Vergin K.L., Lee K., Giovannoni S.J., Cho J.C.;
RT   "Genome sequence of Oceanicaulis sp. strain HTCC2633, isolated from
RT   the Western Sargasso Sea.";
RL   J. Bacteriol. 193:317-318(2011).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EAP89505.1}.
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DR   EMBL; AAMQ01000004; EAP89505.1; -; Genomic_DNA.
DR   RefSeq; WP_009802308.1; NZ_CH672428.1.
DR   ProteinModelPortal; A3UI32; -.
DR   STRING; 314254.OA2633_09574; -.
DR   EnsemblBacteria; EAP89505; EAP89505; OA2633_09574.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006011; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006011};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006011}.
FT   DOMAIN      170    306       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      386    455       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     178    185       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   478 AA;  52415 MW;  00D2FE870C3AEC0B CRC64;
     MGYSQDATAR RDGMDVMDSS SIVTVWRAVR ARLREECGDL VYAAEIARLR VELDAAGRVC
     VICPNEFGRA WVEDNVGVRL RALWASVAEQ ACDIVICTEK TLSSAKSQTV SVAALNAGGV
     SETAALPPAE PVEAEAKREA RFTFDTFMVG SANMMAATAA RAVASADAPP FNPVFFHGDY
     GVGKSHLLAA IAHSASLSGK RKKVLYLTAE EFLNGFQSAL RARDVQPFKD LVRDCDMLLI
     DDVHFICGKP RTEDEFLQTV TALISAEKQV VLASHCAPSQ LSVSDDRLRN ILAGGFNCPL
     QGPDLDLRRK ILDCKIAQAR NHCPDLEVPE TVRDFLAARV TSSARELEGV LNNIIVRTAY
     MNRPVTMETV EEALGELPVK AERRITVDDI QKSVASYFSI TVDDLISKRR TKAVVRPRHI
     AMYLAKTMTT RSLPDIGRRF GGRDHSTVIH AVNKITETLT SDAVLAEDVE ALRRRLRG
//
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