ID   A3Z0F6_9SYNE            Unreviewed;       290 AA.
AC   A3Z0F6;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=tRNA/rRNA methyltransferase (SpoU) {ECO:0000313|EMBL:EAQ74440.1};
GN   ORFNames=WH5701_07421 {ECO:0000313|EMBL:EAQ74440.1};
OS   Synechococcus sp. WH 5701.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC   Synechococcus.
OX   NCBI_TaxID=69042 {ECO:0000313|EMBL:EAQ74440.1, ECO:0000313|Proteomes:UP000002935};
RN   [1] {ECO:0000313|EMBL:EAQ74440.1, ECO:0000313|Proteomes:UP000002935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH5701 {ECO:0000313|Proteomes:UP000002935};
RA   Scanlan D., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA   Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAQ74440.1}.
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DR   EMBL; AANO01000008; EAQ74440.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3Z0F6; -.
DR   eggNOG; COG0566; Bacteria.
DR   HOGENOM; CLU_021322_3_2_3; -.
DR   Proteomes; UP000002935; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR43191; RRNA METHYLTRANSFERASE 3; 1.
DR   PANTHER; PTHR43191:SF2; RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   Pfam; PF08032; SpoU_sub_bind; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
DR   SUPFAM; SSF55315; L30e-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EAQ74440.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002935};
KW   Transferase {ECO:0000313|EMBL:EAQ74440.1}.
FT   DOMAIN          51..125
FT                   /note="RNA 2-O ribose methyltransferase substrate binding"
FT                   /evidence="ECO:0000259|SMART:SM00967"
SQ   SEQUENCE   290 AA;  31208 MW;  02461E8116354426 CRC64;
     MCAAVSRSEA SDGSPWVPQA RELITSRRNP LVGRFRALHQ PRGRREQGLL LLEGTHLLEE
     ALRLGLRPSQ VLASPGWIER HRSLLEGHPR MAALLQPVAE PVLEAVATTA HPDGVVLTLP
     WPEPPACERV DFVLALDRLQ DPGNLGTLMR TALAAGVEEL WHSEGADPFQ PKVLRASAGA
     ALALPCRRLE QLLPRLESAR TGGVQVVASV VAGGIPYWQL DWTLPTVLLL GNEGAGLAPE
     LLAASSHQVT IPHSGAVESL NVAVAAAPLL LERWRQLTGE NAGQQPQQPR
//