ID A4AC35_9GAMM Unreviewed; 498 AA.
AC A4AC35;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 24-JAN-2024, entry version 75.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=KT71_05657 {ECO:0000313|EMBL:EAQ96485.1};
OS Congregibacter litoralis KT71.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae;
OC Congregibacter.
OX NCBI_TaxID=314285 {ECO:0000313|EMBL:EAQ96485.1, ECO:0000313|Proteomes:UP000019205};
RN [1] {ECO:0000313|EMBL:EAQ96485.1, ECO:0000313|Proteomes:UP000019205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT71 {ECO:0000313|EMBL:EAQ96485.1,
RC ECO:0000313|Proteomes:UP000019205};
RX PubMed=17299055; DOI=10.1073/pnas.0608046104;
RA Fuchs B.M., Spring S., Teeling H., Quast C., Wulf J., Schattenhofer M.,
RA Yan S., Ferriera S., Johnson J., Glockner F.O., Amann R.;
RT "Characterization of a marine gammaproteobacterium capable of aerobic
RT anoxygenic photosynthesis.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:2891-2896(2007).
RN [2] {ECO:0000313|EMBL:EAQ96485.1, ECO:0000313|Proteomes:UP000019205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KT71 {ECO:0000313|EMBL:EAQ96485.1,
RC ECO:0000313|Proteomes:UP000019205};
RX PubMed=19287491; DOI=10.1371/journal.pone.0004866;
RA Spring S., Lunsdorf H., Fuchs B.M., Tindall B.J.;
RT "The photosynthetic apparatus and its regulation in the aerobic
RT gammaproteobacterium Congregibacter litoralis gen. nov., sp. nov.";
RL PLoS ONE 4:E4866-E4866(2009).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAQ96485.1}.
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DR EMBL; AAOA02000006; EAQ96485.1; -; Genomic_DNA.
DR RefSeq; WP_008293549.1; NZ_CM002299.1.
DR AlphaFoldDB; A4AC35; -.
DR STRING; 314285.KT71_05657; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_10_6; -.
DR OrthoDB; 5887723at2; -.
DR Proteomes; UP000019205; Chromosome.
DR GO; GO:0018478; F:malonate-semialdehyde dehydrogenase (acetylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:UniProtKB-EC.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF3; METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EAQ96485.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019205}.
FT DOMAIN 15..476
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
SQ SEQUENCE 498 AA; 53710 MW; 1D6ACD8DEF3C4228 CRC64;
MSRKIPLFIN GEFMQGSSDQ TLPVTSPATQ EVLAEVTFAT SREVDFAVAS AKEAFETWRE
VPISDRARLM LRYQALLKEH HDELGEILAK DTGKTFEDAK GDVWRGIEVV EQAANIASAM
MGETVENVAG GIDSYSYIQP LGVCVGITPF NFPAMLPLWM FPMAIACGNT FVLKPSEQVP
MTPVRLVELF MEAGAPKGIL NMVHGGAEQV DQLLNHPDTR SVSFVGSSHV GEHVYKTATA
AGKRVQCMMG AKNHMVIMPD ADKNAVLNAL VGASVGAAGQ RCMAISVAVF VGEAAQWIPE
LAERVAKARP GAWDDGGAAY GPLISKAAHA RVLDLIAKGK SEANCLLDGS DCTVEGMPDG
NWVGPTMFSG VTPEMTIYKE EIFGPVLCCM ELETLDEALA VINANPMGNG TSIFTASGGA
ARKYQHEVAV GQVGINIPIP VPLPFFSFTG WRGSFRGDLH PYGKQAVRFY TETKTVTARW
RYDESEAGKQ PNMSINLR
//
