ID A4AF26_9ACTN Unreviewed; 342 AA.
AC A4AF26;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Regulatory protein, LacI {ECO:0000313|EMBL:EAR26227.1};
GN ORFNames=A20C1_10109 {ECO:0000313|EMBL:EAR26227.1};
OS marine actinobacterium PHSC20C1.
OC Bacteria; Actinomycetota; Actinomycetes.
OX NCBI_TaxID=312284 {ECO:0000313|EMBL:EAR26227.1, ECO:0000313|Proteomes:UP000003868};
RN [1] {ECO:0000313|EMBL:EAR26227.1, ECO:0000313|Proteomes:UP000003868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHSC20C1 {ECO:0000313|EMBL:EAR26227.1,
RC ECO:0000313|Proteomes:UP000003868};
RA Murray A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAR26227.1}.
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DR EMBL; AAOB01000001; EAR26227.1; -; Genomic_DNA.
DR AlphaFoldDB; A4AF26; -.
DR STRING; 312284.A20C1_10109; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_11; -.
DR OrthoDB; 4268837at2; -.
DR Proteomes; UP000003868; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000003868};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..67
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 342 AA; 36541 MW; 88B5BAF6BB446D16 CRC64;
MTASVRQTRP AQPTLEMVAA EAGVSRATVS RVVNGSTKVN PEIVAAVNAA VELLHYLPNR
AARSLANRRT QALALVVPED MTRFFGDPYF AAIVQGITRR LDESDYTLNL LVASSDPQHK
TMRYLRSGSA DGALIISHHT GDDFVAELET TMPVVFGGRP EDDSDTDAYF VDVDNAEGAE
TGTQHLVDIG RRRIGSITGP VDMSAGIDRF TGFLRTLTRA GLATDAIEHA DFSVAGAAAA
TRKLLERCPD IDALFVASDL MATGVLDVLR EQGRVVPRDV AIVGFDDSPA AASAAVPLTT
VSQPSEEMGF AMADTLLRLL SGDTTVPHRT IMPTYLVVRD SA
//
