ID   A4AII3_9ACTN            Unreviewed;       265 AA.
AC   A4AII3;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=Regulator of SigK {ECO:0000256|ARBA:ARBA00030803};
DE   AltName: Full=Sigma-K anti-sigma factor RskA {ECO:0000256|ARBA:ARBA00029829};
GN   ORFNames=A20C1_06741 {ECO:0000313|EMBL:EAR24958.1};
OS   marine actinobacterium PHSC20C1.
OC   Bacteria; Actinomycetota; Actinomycetes.
OX   NCBI_TaxID=312284 {ECO:0000313|EMBL:EAR24958.1, ECO:0000313|Proteomes:UP000003868};
RN   [1] {ECO:0000313|EMBL:EAR24958.1, ECO:0000313|Proteomes:UP000003868}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PHSC20C1 {ECO:0000313|EMBL:EAR24958.1,
RC   ECO:0000313|Proteomes:UP000003868};
RA   Murray A., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA   Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL   Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC       Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAR24958.1}.
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DR   EMBL; AAOB01000005; EAR24958.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4AII3; -.
DR   STRING; 312284.A20C1_06741; -.
DR   eggNOG; COG5343; Bacteria.
DR   HOGENOM; CLU_075802_1_0_11; -.
DR   OrthoDB; 153510at2; -.
DR   Proteomes; UP000003868; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.10.1320; Anti-sigma factor, zinc-finger domain; 1.
DR   InterPro; IPR018764; Anti-sigma_K_RskA.
DR   InterPro; IPR041916; Anti_sigma_zinc_sf.
DR   PANTHER; PTHR37461; ANTI-SIGMA-K FACTOR RSKA; 1.
DR   PANTHER; PTHR37461:SF1; ANTI-SIGMA-K FACTOR RSKA; 1.
DR   Pfam; PF10099; RskA; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003868};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   265 AA;  27291 MW;  08A3CE20640E1F6F CRC64;
     MTERNDDLAA QSGAYALNAL SPEEREAFEK HLTASAETRT ETTELSDTAV ALGMAVDPVT
     PPPALKANLM AMIAQTPQLP REVEVVDDAA KVVQPAATPA EKKAQGRWFT RPATALAAVA
     AAVALIVAGG VVADSIGRTS LQETSFAAQQ ADQLAAINGA SDSQRLVSTV TGGATATFVW
     SVELASSAVI VDGLEPLPDN QVYELWYIDS AGARPAGLMD ASTDGTTWRV LDGKMAAGDV
     VGVTIEPKGG SDAPTTAPIV VFESA
//