ID A4D1Y2_HUMAN Unreviewed; 387 AA.
AC A4D1Y2;
DT 03-APR-2007, integrated into UniProtKB/TrEMBL.
DT 03-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Similar to cell division cycle 10 homolog {ECO:0000313|EMBL:EAL23974.1};
GN Name=LOC392884 {ECO:0000313|EMBL:EAL23974.1};
GN ORFNames=tcag7.1317 {ECO:0000313|EMBL:EAL23974.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:EAL23974.1};
RN [1] {ECO:0000313|EMBL:EAL23974.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12690205; DOI=10.1126/science.1083423;
RA Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K.,
RA Herbrick J.A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R.,
RA Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A.,
RA Kanematsu E., Gentles S., Christopoulos C.C., Choufani S., Kwasnicka D.,
RA Zheng X.H., Lai Z., Nusskern D., Zhang Q., Gu Z., Lu F., Zeesman S.,
RA Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R.,
RA Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N.,
RA Friedman J.M., Heng H.H., Pelicci P.G., Lo-Coco F., Belloni E.,
RA Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A., Korf B.R.,
RA Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T.,
RA Herrick S.R., Lemyre E., Farra C.G., Kim H.G., Summers A.M., Gripp K.W.,
RA Roberts W., Szatmari P., Winsor E.J., Grzeschik K.H., Teebi A.,
RA Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X.,
RA Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E.,
RA Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Dohner H.,
RA Dohner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J.,
RA Adams M.D., Tsui L.C.;
RT "Human chromosome 7: DNA sequence and biology.";
RL Science 300:767-772(2003).
RN [2] {ECO:0000313|EMBL:EAL23974.1}
RP NUCLEOTIDE SEQUENCE.
RA Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K.,
RA Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R.,
RA Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A.,
RA Kanematsu E., Gentles S., Christopoulos C.C., Choufani S., Kwasnicka D.,
RA Zheng X.H., Nusskern D., Zhang Q., Gu Z., Lu F., Zeesman S., Teshima I.,
RA Chitayat D., Shuman C., Weksberg R., Zackai E.H., Grebe T.A., Cox S.R.,
RA Kirkpatrick S.J., Rahman N., Friedman J.M., Heng H.H.Q., Pelicci P.,
RA Lococo F., Belloni E., Shaffer L.G., Morton C.C., Pober B., Gusella J.,
RA Bruns G., Korf B.R., Quade B.J., Ligon A.H., Ferguson H., Higgins A.W.,
RA Leach N.T., Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M.,
RA Gripp K.W., Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H.,
RA Teebi A., Minassian B.A., Kere J., Armengol L., Pujana M.Angel.,
RA Estivill X., Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P.,
RA Zlotorynski E., Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J.,
RA Doehner H., Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W.,
RA Mural R.J., Adams M.D., Tsui L.-C.;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR EMBL; CH236951; EAL23974.1; -; Genomic_DNA.
DR AlphaFoldDB; A4D1Y2; -.
DR MaxQB; A4D1Y2; -.
DR PeptideAtlas; A4D1Y2; -.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR041156; DUF5533.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48343; TRANSMEMBRANE PROTEIN 250; 1.
DR PANTHER; PTHR48343:SF1; TRANSMEMBRANE PROTEIN 250; 1.
DR Pfam; PF17685; DUF5533; 2.
DR Pfam; PF00735; Septin; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:EAL23974.1};
KW Cell division {ECO:0000313|EMBL:EAL23974.1};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU004560}.
FT DOMAIN 19..105
FT /note="Septin-type G"
FT /evidence="ECO:0000259|Pfam:PF00735"
FT COILED 338..383
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 387 AA; 44848 MW; 3016F0135D601F97 CRC64;
MAQERPPIPT AEIPVAADKE IQEHNVKIHE FPETDDEEEK KLVKKIKDHL PLAVVGSNTI
IEVNGKRVIG RQYPWSVAEE HTQDLKDVTN NVHYENYGIR KLAAVTYHGV DNKKNKGQFA
KSPLAQMEEE RREQVAKIKK MEMEMEQVFE MKVKEKVQKL KDSEAELGRR CRRGPMPVMP
IPRGLCSFHG PHTTCLHAVC GPVGASHLAR TKYNSFEYLG VSVLLCFQHK LWVLLLLLGR
WRVEFRLVNE LLIYSIHVTM LLDGGLGWCL MVFVDIPGIV SLHVQELIHI NLQFWDLLFL
AVAEAPPPDL PLIRLGRRDH EHASGRSLRR RLREAGRLAL LQRRHEQMKK NLEAQHKELE
EKRRQFEDEK ANWEAQQRIL EQQNSSR
//
