ID   A4F7M0_SACEN            Unreviewed;       316 AA.
AC   A4F7M0;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   RecName: Full=HTH cro/C1-type domain-containing protein {ECO:0000259|SMART:SM00530};
GN   OrderedLocusNames=SACE_0702 {ECO:0000313|EMBL:CAM00044.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM00044.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAM00044.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
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DR   EMBL; AM420293; CAM00044.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4F7M0; -.
DR   KEGG; sen:SACE_0702; -.
DR   eggNOG; ENOG502ZWBP; Bacteria.
DR   HOGENOM; CLU_879657_0_0_11; -.
DR   OrthoDB; 9815928at2; -.
DR   Proteomes; UP000006728; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF13560; HTH_31; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        189..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          14..66
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000259|SMART:SM00530"
FT   REGION          89..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   316 AA;  34292 MW;  7A55BE56B6D5F17C CRC64;
     MEQRHPDIGR WSGRLQELAE ATGLSLRQLS EHVPWSPSTL SRYLSGERVV DEAWLLASKL
     IDLAHRRGTP VDVRSDELHL LYQQARKAYQ QQRRSARGKA DQVGESAATA PTSSDVGLPE
     RPAEQPVVAS SGQPNATEPA TDSSEQPNAT PPAPSPDTPA TATSEQSDAA PEPPSSPDAR
     PARRSRRPFV LALATAVAVA AVAAAVWASL LWLRPQTVVW RANIVGTWSA QHQQHLGVFR
     FRTPDVPGDT DKATYHEGTA VSIVCQARHR RVVSDPTTGQ SSPVWNRLSD GYWIPDLYTD
     LPKVTGEAPP LGIPLC
//