ID A4F860_SACEN Unreviewed; 469 AA.
AC A4F860;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=IS30 family transposase {ECO:0000313|EMBL:PFG94029.1};
DE SubName: Full=Transposase, ISlxx5 {ECO:0000313|EMBL:CAM00235.1};
GN Name=tnp {ECO:0000313|EMBL:CAM00235.1};
GN OrderedLocusNames=SACE_0901 {ECO:0000313|EMBL:CAM00235.1};
GN ORFNames=A8924_1295 {ECO:0000313|EMBL:PFG94029.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM00235.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM00235.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM00235.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG94029.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG94029.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the transposition of the insertion element.
CC {ECO:0000256|ARBA:ARBA00002190}.
CC -!- SIMILARITY: Belongs to the transposase IS30 family.
CC {ECO:0000256|ARBA:ARBA00006363}.
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DR EMBL; AM420293; CAM00235.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG94029.1; -; Genomic_DNA.
DR AlphaFoldDB; A4F860; -.
DR KEGG; sen:SACE_0901; -.
DR eggNOG; COG2826; Bacteria.
DR HOGENOM; CLU_035706_0_0_11; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006313; P:DNA transposition; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR025246; IS30-like_HTH.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR001598; Transposase_IS30_CS.
DR NCBIfam; NF033563; transpos_IS30; 1.
DR PANTHER; PTHR10948; TRANSPOSASE; 1.
DR PANTHER; PTHR10948:SF23; TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED; 1.
DR Pfam; PF13936; HTH_38; 1.
DR Pfam; PF00665; rve; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS01043; TRANSPOSASE_IS30; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT DOMAIN 311..465
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 469 AA; 52670 MW; DF0441FD83DDE9B8 CRC64;
MGVARTVACE GDSAELKQRF LDRLDAVGSV TVAARELGLN RNTAFGWARQ AGRRSIRASR
RHPRREEYER LRSEGVARRR AAERVGINER TAKDWDYGVR KSRNARTYPN GVRVDYAAGT
STIVDVNSVA PKLSALDKQL HPRLLTLVER ERIRDLRAEG HSLRAIGKAL GRSASTILRE
IRANSTHGAY RPYAAHRAAA ARRPRPKQRK LIAQGPLRQF VVDGLRKRWS PEQICHALGK
EHPGDQRMRV SVETIYQALY FQARGGLKRE VQAAIRTGRT RRKPRRNPNQ RTARFIDPMV
MISDRPAEVE DRAVPGHWEG DLIIGAGSQS AIGTLVERTT RYTMLVHLPN GHDAEAVRDG
LVATITTLPT HLRGSLTWDQ GAEMARHKQF TMATDMPVYF CDPASPWQRG SNENTNGLLR
QYFPKGTDLG TYGPEDLEHV AQQLNGRPRK TLGWDSPAER LAMLLTEAS
//
