ID A4FFF5_SACEN Unreviewed; 482 AA.
AC A4FFF5;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Iron-sulfur cluster binding protein {ECO:0000313|EMBL:CAM02780.1};
DE SubName: Full=L-lactate dehydrogenase complex protein LldF {ECO:0000313|EMBL:PFG96501.1};
GN OrderedLocusNames=SACE_3506 {ECO:0000313|EMBL:CAM02780.1};
GN ORFNames=A8924_3899 {ECO:0000313|EMBL:PFG96501.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM02780.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM02780.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM02780.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG96501.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG96501.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AM420293; CAM02780.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG96501.1; -; Genomic_DNA.
DR AlphaFoldDB; A4FFF5; -.
DR STRING; 405948.SACE_3506; -.
DR KEGG; sen:SACE_3506; -.
DR eggNOG; COG0247; Bacteria.
DR eggNOG; COG1139; Bacteria.
DR HOGENOM; CLU_027059_1_0_11; -.
DR OrthoDB; 9782337at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019516; P:lactate oxidation; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.40.50.10420; NagB/RpiA/CoA transferase-like; 1.
DR InterPro; IPR004452; 4Fe-4S-bd.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR024185; FTHF_cligase-like_sf.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR003741; LUD_dom.
DR InterPro; IPR024569; LutB_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR00273; LutB/LldF family L-lactate oxidation iron-sulfur protein; 1.
DR PANTHER; PTHR47153; LACTATE UTILIZATION PROTEIN B; 1.
DR PANTHER; PTHR47153:SF2; LACTATE UTILIZATION PROTEIN B; 1.
DR Pfam; PF13183; Fer4_8; 1.
DR Pfam; PF02589; LUD_dom; 1.
DR Pfam; PF11870; LutB_C; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
PE 4: Predicted;
KW Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 70..297
FT /note="LUD"
FT /evidence="ECO:0000259|Pfam:PF02589"
FT DOMAIN 314..383
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|Pfam:PF13183"
FT DOMAIN 396..475
FT /note="Lactate utilization protein B C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11870"
SQ SEQUENCE 482 AA; 52469 MW; FA85271524A1F6E8 CRC64;
MSTFLGMPPF PEAAKRAVAD SQLRHNLAGA TATIRRKRAS VVGELDDWAE LREAGAAIKA
HTLSHLDTYL ERFEAAVTAA GGVVHWARDA EEANRIVVDL VRATGEREVV KVKSMATQEI
ELNEALGDAG ISAWETDLAE LIVQLGNDAP SHILVPAIHR NRAEVREIFR REMGGAGVPA
PDDLTDEPAR LADVARRHLR EKFLRAKVAV SGVNFAVADT GTLVVVESEG NGRMCLTLPE
TLISVVGIEK LVPSWRDLEV FLQLLPRSST GERMNPYTST WTGVTPGDGP QSFHVVLLDN
GRTNALADEV GRQALRCIRC SACLNVCPVY ERTGGHAYGS VYPGPIGAVL TPQLRGTASP
VDQALPYASS LCGACYDVCP VAIDIPDLLV HLRTRVVEEH HGVRSRPLDL LMGLASWVLG
DARRLAAVQR VASWSRRFIG RRGTIGRLPA PLSRWTDARD APAPARESFR AWWERTRGGK
QP
//
