ID A4FKQ1_SACEN Unreviewed; 201 AA.
AC A4FKQ1;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Leucine responsive regulator {ECO:0000313|EMBL:CAM04626.1};
GN Name=lrp {ECO:0000313|EMBL:CAM04626.1};
GN OrderedLocusNames=SACE_5388 {ECO:0000313|EMBL:CAM04626.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM04626.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM04626.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
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DR EMBL; AM420293; CAM04626.1; -; Genomic_DNA.
DR AlphaFoldDB; A4FKQ1; -.
DR STRING; 405948.SACE_5388; -.
DR KEGG; sen:SACE_5388; -.
DR eggNOG; COG1522; Bacteria.
DR HOGENOM; CLU_091233_0_3_11; -.
DR Proteomes; UP000006728; Chromosome.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.70.920; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR011008; Dimeric_a/b-barrel.
DR InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30154; LEUCINE-RESPONSIVE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30154:SF34; TRANSCRIPTIONAL REGULATOR AZLB; 1.
DR Pfam; PF01037; AsnC_trans_reg; 1.
DR Pfam; PF13412; HTH_24; 1.
DR PRINTS; PR00033; HTHASNC.
DR SMART; SM00344; HTH_ASNC; 1.
DR SUPFAM; SSF54909; Dimeric alpha+beta barrel; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00519; HTH_ASNC_1; 1.
DR PROSITE; PS50956; HTH_ASNC_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 56..117
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|PROSITE:PS50956"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 201 AA; 22239 MW; 26BD8E3E09702F36 CRC64;
MPAAMRSRRE AEGEGEGTAS GESSTGCCTC PCSRNTRGVW LRTLPARAAS GQHSRMDKLD
RAIIAELERD GRLTNVELAG RVGLTPGPCL RRVQRLESDG VIRGYRAVTD PAHLGRSFEV
LLEVTLEAQD ARTVEHFEAT MAGFSVVREL RRLFGAPDYF VRVAVADLDA YETFLSRHVM
TIPKVARVTS RFTMKTLKQL D
//
