ID A4FMB9_SACEN Unreviewed; 467 AA.
AC A4FMB9;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=DNA-binding PucR family transcriptional regulator {ECO:0000313|EMBL:PFG98841.1};
DE SubName: Full=Regulatory protein {ECO:0000313|EMBL:CAM05194.1};
GN OrderedLocusNames=SACE_6020 {ECO:0000313|EMBL:CAM05194.1};
GN ORFNames=A8924_6367 {ECO:0000313|EMBL:PFG98841.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM05194.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM05194.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM05194.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG98841.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG98841.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CdaR family.
CC {ECO:0000256|ARBA:ARBA00006754}.
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DR EMBL; AM420293; CAM05194.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG98841.1; -; Genomic_DNA.
DR RefSeq; WP_011874917.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4FMB9; -.
DR STRING; 405948.SACE_6020; -.
DR KEGG; sen:SACE_6020; -.
DR eggNOG; COG2508; Bacteria.
DR HOGENOM; CLU_017436_4_1_11; -.
DR OrthoDB; 3170447at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.2840; PucR C-terminal helix-turn-helix domain; 1.
DR InterPro; IPR041522; CdaR_GGDEF.
DR InterPro; IPR025736; PucR_C-HTH_dom.
DR InterPro; IPR042070; PucR_C-HTH_sf.
DR InterPro; IPR012914; PucR_dom.
DR PANTHER; PTHR33744; CARBOHYDRATE DIACID REGULATOR; 1.
DR PANTHER; PTHR33744:SF1; CONSERVED PROTEIN; 1.
DR Pfam; PF17853; GGDEF_2; 1.
DR Pfam; PF13556; HTH_30; 1.
DR Pfam; PF07905; PucR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:PFG98841.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT DOMAIN 20..118
FT /note="Purine catabolism PurC-like"
FT /evidence="ECO:0000259|Pfam:PF07905"
FT DOMAIN 252..352
FT /note="CdaR GGDEF-like"
FT /evidence="ECO:0000259|Pfam:PF17853"
FT DOMAIN 405..463
FT /note="PucR C-terminal helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF13556"
SQ SEQUENCE 467 AA; 50575 MW; 7C6060D09493225A CRC64;
MLVDDLLGKP ELALETRVRG NTQRPIRWVH TIEVRAPGRF LRGGEVVLTA GVWRAAGVTA
RDFVADLVEA DVAAVGFGPV PPELQVPDEF VDAAREHGLT CFVVPVDVAF LQVVEAFVST
KRAEWERPLR RHLGQHDAIV AALRVHRGVT TVLRTLSGQL GLPVAVRVDG GLVEGEAPRP
QYPLPLVGEG LAEAELLLPR PLEELDVEQQ AAVVQAMPFI ALEIERNRAV RATELRYAWE
LFEWVHTGAV GPETVRTRLH SLGLPSDGPL AAVVVRSANP DVDAVRLGEL LGSDGVAVQR
GGEAVAFARV RDTTADLARR VHEALGAHVG AGKPGTAGDL RVSLLQASHA AEAVSGRADG
GWMTHEQLSS PSLLLSAQDP ELLVSTSRAL LGPVLDHDER RGGDLLPSLW VFLDAGCRWQ
ESAQRLHVHI NTLRHRMSRV EELTGRSLSS TADRVDLFLA LRALRQS
//
