ID A4FQS9_SACEN Unreviewed; 227 AA.
AC A4FQS9;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=NADP-dependent 3-hydroxy acid dehydrogenase YdfG {ECO:0000313|EMBL:PFG93006.1};
DE SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:CAM06404.1};
GN OrderedLocusNames=SACE_7246 {ECO:0000313|EMBL:CAM06404.1};
GN ORFNames=A8924_0231 {ECO:0000313|EMBL:PFG93006.1};
OS Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=405948 {ECO:0000313|EMBL:CAM06404.1, ECO:0000313|Proteomes:UP000006728};
RN [1] {ECO:0000313|EMBL:CAM06404.1, ECO:0000313|Proteomes:UP000006728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC {ECO:0000313|EMBL:CAM06404.1};
RX PubMed=17369815; DOI=10.1038/nbt1297;
RA Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA Haydock S.F., Leadlay P.F.;
RT "Complete genome sequence of the erythromycin-producing bacterium
RT Saccharopolyspora erythraea NRRL23338.";
RL Nat. Biotechnol. 25:447-453(2007).
RN [2] {ECO:0000313|EMBL:PFG93006.1, ECO:0000313|Proteomes:UP000225825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93006.1,
RC ECO:0000313|Proteomes:UP000225825};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
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DR EMBL; AM420293; CAM06404.1; -; Genomic_DNA.
DR EMBL; PDBV01000001; PFG93006.1; -; Genomic_DNA.
DR RefSeq; WP_009944481.1; NZ_PDBV01000001.1.
DR AlphaFoldDB; A4FQS9; -.
DR STRING; 405948.SACE_7246; -.
DR KEGG; sen:SACE_7246; -.
DR eggNOG; COG4221; Bacteria.
DR HOGENOM; CLU_010194_2_10_11; -.
DR OrthoDB; 158573at2; -.
DR Proteomes; UP000006728; Chromosome.
DR Proteomes; UP000225825; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR44196; DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B; 1.
DR PANTHER; PTHR44196:SF5; POSSIBLE MULTI-FUNCTIONAL ENZYME WITH ACYL-COA-REDUCTASE ACTIVITY ACRA1; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006728}.
SQ SEQUENCE 227 AA; 24042 MW; E1CA1B79A41C6B47 CRC64;
MPERPIALVT GASRGIGAAV ARSLADTHDL LLGGRDTTAL EKVTADIPGA RPWPVELTDH
ESVAAAVAEI DRLDVLVHSA GLVELAPVAD APPDSWRRTF ELNLFAVTEL TRLLLPALRA
AKGHVVLVNS GAGLSAKPNW GSYAASKFAL RAFADVLRAE EAASGVRVTS VFPGRTATEM
QRGVRAAEGG EFEPENYLRP ESVAEPIVSA VRSSRDAHMT ELVIRPA
//
