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Database: UniProt
Entry: A4G687_HERAR
LinkDB: A4G687_HERAR
Original site: A4G687_HERAR 
ID   A4G687_HERAR            Unreviewed;       251 AA.
AC   A4G687;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   05-JUL-2017, entry version 60.
DE   RecName: Full=Flagellar brake protein YcgR {ECO:0000256|HAMAP-Rule:MF_01457};
DE   AltName: Full=Cyclic di-GMP binding protein YcgR {ECO:0000256|HAMAP-Rule:MF_01457};
GN   Name=ycgR {ECO:0000256|HAMAP-Rule:MF_01457};
GN   OrderedLocusNames=HEAR1873 {ECO:0000313|EMBL:CAL62024.1};
OS   Herminiimonas arsenicoxydans.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Oxalobacteraceae; Herminiimonas.
OX   NCBI_TaxID=204773 {ECO:0000313|EMBL:CAL62024.1, ECO:0000313|Proteomes:UP000006697};
RN   [1] {ECO:0000313|EMBL:CAL62024.1, ECO:0000313|Proteomes:UP000006697}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ULPAs1 {ECO:0000313|Proteomes:UP000006697};
RX   PubMed=17432936; DOI=10.1371/journal.pgen.0030053;
RA   Muller D., Medigue C., Koechler S., Barbe V., Barakat M., Talla E.,
RA   Bonnefoy V., Krin E., Arsene-Ploetze F., Carapito C., Chandler M.,
RA   Cournoyer B., Cruveiller S., Dossat C., Duval S., Heymann M.,
RA   Leize E., Lieutaud A., Lievremont D., Makita Y., Mangenot S.,
RA   Nitschke W., Ortet P., Perdrial N., Schoepp B., Siguier N.,
RA   Simeonova D.D., Rouy Z., Segurens B., Turlin E., Vallenet D.,
RA   Van Dorsselaer A., Weiss S., Weissenbach J., Lett M.C., Danchin A.,
RA   Bertin P.N.;
RT   "A tale of two oxidation states: bacterial colonization of arsenic-
RT   rich environments.";
RL   PLoS Genet. 3:518-530(2007).
CC   -!- FUNCTION: Acts as a flagellar brake, regulating swimming and
CC       swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-
CC       dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing
CC       levels of c-di-GMP lead to decreased motility. {ECO:0000256|HAMAP-
CC       Rule:MF_01457}.
CC   -!- SUBUNIT: Monomer. Interacts with the flagellar basal bodies.
CC       {ECO:0000256|HAMAP-Rule:MF_01457}.
CC   -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body
CC       {ECO:0000256|HAMAP-Rule:MF_01457}.
CC   -!- SIMILARITY: Belongs to the YcgR family. {ECO:0000256|HAMAP-
CC       Rule:MF_01457}.
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DR   EMBL; CU207211; CAL62024.1; -; Genomic_DNA.
DR   RefSeq; WP_011871349.1; NC_009138.1.
DR   STRING; 204773.HEAR1873; -.
DR   EnsemblBacteria; CAL62024; CAL62024; HEAR1873.
DR   KEGG; har:HEAR1873; -.
DR   eggNOG; ENOG4108T7K; Bacteria.
DR   eggNOG; COG5581; LUCA.
DR   HOGENOM; HOG000254650; -.
DR   OMA; RYIFRID; -.
DR   OrthoDB; POG091H0NAE; -.
DR   Proteomes; UP000006697; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0048037; F:cofactor binding; IEA:InterPro.
DR   GO; GO:0035438; F:cyclic-di-GMP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-HAMAP.
DR   GO; GO:0071945; P:regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed; IEA:UniProtKB-HAMAP.
DR   Gene3D; 2.30.110.10; -; 1.
DR   HAMAP; MF_01457; YcgR; 1.
DR   InterPro; IPR009875; PilZ_domain.
DR   InterPro; IPR012349; Split_barrel_FMN-bd.
DR   InterPro; IPR023787; T3SS_YcgR.
DR   InterPro; IPR009926; T3SS_YcgR_N.
DR   Pfam; PF07238; PilZ; 1.
DR   Pfam; PF07317; YcgR; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum {ECO:0000256|HAMAP-Rule:MF_01457};
KW   c-di-GMP {ECO:0000256|HAMAP-Rule:MF_01457};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006697};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01457};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006697}.
FT   DOMAIN       15    121       T3SS_YcgR_N. {ECO:0000259|Pfam:PF07317}.
FT   DOMAIN      123    237       PilZ. {ECO:0000259|Pfam:PF07238}.
SQ   SEQUENCE   251 AA;  27781 MW;  3258B04F28149D3B CRC64;
     MTLASEYEND DLNPYRVNSR REVIALLRSI GERNQLVRML INHGNDTIVT SILQIDETAN
     TVLLDCAPTA IMNQRVLNSE KLSFETVLEN IRILFNSPAA QSCIYENLPA FIIPLPTSVI
     RLQRREFYRV STPVTNPVYC TIPVKTEDQI IPVVVPLHNI SGGGLSVVDE KKLIDSTPGR
     IYENCRLDLP GGVVTLALQV RNQLEVTLTN GKSIHRLGCA FVDPSNGALA AVQKYITKLE
     RDQNAKATGL G
//
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