ID A4GW13_CERAT Unreviewed; 211 AA.
AC A4GW13;
DT 17-APR-2007, integrated into UniProtKB/TrEMBL.
DT 17-APR-2007, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Programmed cell death ligand 2 {ECO:0000313|EMBL:ABO33145.1};
OS Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Cercocebus.
OX NCBI_TaxID=9531 {ECO:0000313|EMBL:ABO33145.1};
RN [1] {ECO:0000313|EMBL:ABO33145.1}
RP NUCLEOTIDE SEQUENCE.
RA Onlamoon N., Rogers K., Mayne A.E., Pattanapanyasat K., Mori K.,
RA Villinger F., Ansari A.A.;
RT "Studies of the expression of PD-1 on CD4+ and CD8+ T cells and its subsets
RT in SIV infected disease susceptible rhesus macaques and SIV infected
RT disease resistant sooty mangabeys.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; EF444798; ABO33145.1; -; mRNA.
DR AlphaFoldDB; A4GW13; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0002682; P:regulation of immune system process; IEA:UniProt.
DR CDD; cd20983; IgV_PD-L2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR25466:SF1; PROGRAMMED CELL DEATH 1 LIGAND 2; 1.
DR PANTHER; PTHR25466; T-LYMPHOCYTE ACTIVATION ANTIGEN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..211
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002669450"
FT DOMAIN 133..205
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 211 AA; 23786 MW; BA7600AD7370E6B3 CRC64;
MIFLLLMLSL ELQLHQTAAL FTVTVPKELY IIEHGSNVTL ECNFDTGSHV NLGAITASLQ
KVENDTSPHR ERATLLEEQL SLGKALFHIP QVQVRDEGQY QCIIIYGVAW DYKYLTLKVK
ASYRKINTHI LKVPETDEVE LTCQATGYPL AEVSWPNISV PANTSHSRTP EGLYQVTSVL
RLKPHPGRNF SCVSWNAQTQ QKDLSPRKKG K
//
