ID A4HBE7_LEIBR Unreviewed; 410 AA.
AC A4HBE7;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAM38733.1};
GN ORFNames=LBRM_20_3870 {ECO:0000313|EMBL:CAM38733.1};
OS Leishmania braziliensis.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania;
OC Leishmania braziliensis species complex.
OX NCBI_TaxID=5660 {ECO:0000313|EMBL:CAM38733.1, ECO:0000313|Proteomes:UP000007258};
RN [1] {ECO:0000313|EMBL:CAM38733.1, ECO:0000313|Proteomes:UP000007258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM38733.1,
RC ECO:0000313|Proteomes:UP000007258};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR798994; CAM38733.1; -; Genomic_DNA.
DR RefSeq; XP_001564667.1; XM_001564617.1.
DR AlphaFoldDB; A4HBE7; -.
DR STRING; 5660.A4HBE7; -.
DR GeneID; 5415218; -.
DR KEGG; lbz:LBRM_20_3870; -.
DR VEuPathDB; TriTrypDB:LbrM.20.3870; -.
DR VEuPathDB; TriTrypDB:LBRM2903_200053000; -.
DR InParanoid; A4HBE7; -.
DR OMA; YICNDQA; -.
DR Proteomes; UP000007258; Chromosome 20.
DR CDD; cd00027; BRCT; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Reference proteome {ECO:0000313|Proteomes:UP000007258}.
FT DOMAIN 22..75
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 245..307
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 111..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..236
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 44159 MW; 60C1309AF1477981 CRC64;
MNATAYALVA QEKQYPLQLG KNVVGRSSVP VEGVSFINLE SPLAAISRMQ AFLDIGANGD
AWLSDCNSTN GTFLSVRPGP GIRLEANRYY QLSPGCRIVF GDVECTFETL SGAPPTPEHR
ARPLTSPSTP TRKTESLGVV EALTDSATKT TPVRYPWKHA DAHRSNIPYL DESGSLSLKP
AAWDETTGMT KQAPRRERPA PTAPAQPLKR SKVESVAASS SPKLKTTPSA KSTAAGLARA
ARPHVCLTGM DSDERAAIAK RVRELKGRVV EDITKANLLV VATPPVRTPK LIIAVARGIP
VVSVEYICNG KTELDDARHH IVDLKTEQHT YTAAALKKVI YRKDACPLLR GVSFNIAALS
TKTKSVAAEI ITFSGGEVVR AKKGGDFVLT DALLDRLYDS ILRGKVPDAW
//
