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Database: UniProt
Entry: A4HCD6_LEIBR
LinkDB: A4HCD6_LEIBR
Original site: A4HCD6_LEIBR 
ID   A4HCD6_LEIBR            Unreviewed;       664 AA.
AC   A4HCD6;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 2.
DT   25-OCT-2017, entry version 48.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAM45119.2};
GN   ORFNames=LBRM_22_0730 {ECO:0000313|EMBL:CAM45119.2};
OS   Leishmania braziliensis.
OC   Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae;
OC   Leishmaniinae; Leishmania; Leishmania braziliensis species complex.
OX   NCBI_TaxID=5660 {ECO:0000313|Proteomes:UP000007258};
RN   [1] {ECO:0000313|EMBL:CAM45119.2, ECO:0000313|Proteomes:UP000007258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM45119.2,
RC   ECO:0000313|Proteomes:UP000007258};
RX   PubMed=17572675; DOI=10.1038/ng2053;
RA   Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA   Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA   Fraser A., Rajandream M.-A., Carver T., Norbertczak H.,
RA   Chillingworth T., Hance Z., Jagels K., Moule S., Ormond D., Rutter S.,
RA   Sqaures R., Whitehead S., Rabbinowitsch E., Arrowsmith C., White B.,
RA   Thurston S., Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D.,
RA   Depledge D.P., Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R.O.,
RA   Barrell B., Cruz A.K., Mottram J.C., Smith D.F., Berriman M.;
RT   "Comparative genomic analysis of three Leishmania species that cause
RT   diverse human disease.";
RL   Nat. Genet. 39:839-847(2007).
RN   [2] {ECO:0000313|EMBL:CAM45119.2, ECO:0000313|Proteomes:UP000007258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/BR/75/M2904 {ECO:0000313|EMBL:CAM45119.2,
RC   ECO:0000313|Proteomes:UP000007258};
RX   PubMed=22038252; DOI=10.1101/gr.122945.111;
RA   Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA   Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA   Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA   Hertz-Fowler C., Mottram J.C.;
RT   "Chromosome and gene copy number variation allow major structural
RT   change between species and strains of Leishmania.";
RL   Genome Res. 21:2129-2142(2011).
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DR   EMBL; FR798997; CAM45119.2; -; Genomic_DNA.
DR   RefSeq; XP_001564992.2; XM_001564942.2.
DR   EnsemblProtists; CAM45119; CAM45119; LBRM_22_0730.
DR   GeneDB; LbrM.22.0730:pep; -.
DR   GeneID; 5415558; -.
DR   KEGG; lbz:LBRM_22_0730; -.
DR   eggNOG; ENOG410K2HK; Eukaryota.
DR   eggNOG; ENOG4110F5V; LUCA.
DR   InParanoid; A4HCD6; -.
DR   Proteomes; UP000007258; Chromosome 22.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR   Gene3D; 1.10.245.10; -; 1.
DR   Gene3D; 2.30.130.10; -; 1.
DR   Gene3D; 3.30.780.10; -; 1.
DR   InterPro; IPR015947; PUA-like_domain.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR001950; SUI1.
DR   InterPro; IPR036877; SUI1_dom_sf.
DR   InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR   Pfam; PF01253; SUI1; 1.
DR   SUPFAM; SSF55159; SSF55159; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   PROSITE; PS50296; SUI1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007258};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007258}.
FT   DOMAIN      571    652       SUI1. {ECO:0000259|PROSITE:PS50296}.
SQ   SEQUENCE   664 AA;  74277 MW;  2F87DE654DB38321 CRC64;
     MFKKKCTTKE AQSISKSDVK KLRADVVDVI GKNSADKFDL VVRKKDTVTK RKYQCGSGSS
     VFVYSVNEVP FFISIDRLGK EEHNVITEAR PFSFLIVPTI FFFLRLHQLL AEKGDEWTSV
     VNEVGVAIIC RGPTSRFILS GAHLMMPGIL STRKKTPVSA GDVALIYSLG VDVPYAIGIV
     TSSMAARQDT GVGVFVVQCF RDSLWQEFEN RFITNYSLSS ELFLIPSEFE EDQVREKLSE
     MGVATTENEN TNHHVFNNEV TEGNEAPGVD YTDIFSDVDR VLKFCLCEAV KQVSHSLLPM
     PMQQFTSIVV HSYPRDGAHT SAIQFKDTKY KKALTFFQGF PDLLTVVETS PCVYCVTQVT
     KSADLMRQHN ALYADFLSTV HMEGCRKEAQ ELQAKLLADG AGVFRQCIVS ASVFYAAPRS
     LDDDLIRILL LGEELNIPRD SLFPTIEHAT TGTVPIFEKA PIDDSVLQEI YTQKTLVDNL
     KNYIKAHNLL VVSDSEKGKL PRVKIDDVLS MMFTFKAYTS EMPLDQVKQG MLRLFRLKHE
     IVLQTVVEGA SLASDNLIPK RLIKNGPLPK VNLWSEKSTN SKLITIVQNL ESFGFDLELL
     ADQWKKQFST SCGVVDPSTK LKNLKPGTKI PFEIHLQGDL KQKVAAALLK EANLPPSQLI
     CKKK
//
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