ID A4I4G7_LEIIN Unreviewed; 373 AA.
AC A4I4G7; A0A2K4YZD5; A0A381MQB3;
DT 01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 2.
DT 24-JAN-2024, entry version 72.
DE SubName: Full=Putative ribosomal protein L1a {ECO:0000313|EMBL:CAM69676.2};
GN ORFNames=LINJ_29_1160 {ECO:0000313|EMBL:CAM69676.2}, LINJ_29_1170
GN {ECO:0000313|EMBL:CBZ08867.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CAM69676.2, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM69676.2,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CAM69676.2, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM69676.2,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
RN [3] {ECO:0000313|EMBL:CAM69676.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CAM69676.2};
RA Aslett M.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JPCM5;
RA Hilley J.D., Rogers M., Wilkes J., Dickens N.J., Bates P., Depledge D.P.,
RA Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Saad W., Seeger K.,
RA Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow genomic structural
RT differences between species and strains of Leishmania.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC {ECO:0000256|ARBA:ARBA00010528}.
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DR EMBL; FR796461; CAM69676.2; -; Genomic_DNA.
DR EMBL; FR796461; CBZ08867.1; -; Genomic_DNA.
DR RefSeq; XP_001466636.2; XM_001466599.2.
DR RefSeq; XP_003392685.1; XM_003392637.1.
DR AlphaFoldDB; A4I4G7; -.
DR SMR; A4I4G7; -.
DR STRING; 5671.A4I4G7; -.
DR GeneID; 10966072; -.
DR GeneID; 5070669; -.
DR KEGG; lif:LINJ_29_1160; -.
DR KEGG; lif:LINJ_29_1170; -.
DR VEuPathDB; TriTrypDB:LINF_290016800; -.
DR eggNOG; KOG1475; Eukaryota.
DR InParanoid; A4I4G7; -.
DR OrthoDB; 275636at2759; -.
DR Proteomes; UP000008153; Chromosome 29.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 3.40.1370.10; -; 1.
DR InterPro; IPR025755; Ribos_uL4_C_dom.
DR InterPro; IPR002136; Ribosomal_uL4.
DR InterPro; IPR023574; Ribosomal_uL4_dom_sf.
DR InterPro; IPR013000; Ribosomal_uL4_euk/arc_CS.
DR InterPro; IPR045240; Ribosomal_uL4_euk/arch.
DR PANTHER; PTHR19431; 60S RIBOSOMAL PROTEIN L4; 1.
DR PANTHER; PTHR19431:SF0; 60S RIBOSOMAL PROTEIN L4; 1.
DR Pfam; PF14374; Ribos_L4_asso_C; 1.
DR Pfam; PF00573; Ribosomal_L4; 1.
DR SUPFAM; SSF52166; Ribosomal protein L4; 1.
DR PROSITE; PS00939; RIBOSOMAL_L1E; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008153};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000313|EMBL:CAM69676.2}.
FT DOMAIN 273..345
FT /note="Large ribosomal subunit protein uL4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14374"
FT REGION 347..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..373
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 41150 MW; B0C0EF091542FDAB CRC64;
MSARPSVSVY SASSDSVVGT CPLPAVFTAP IRNDIVKFVH TNMAKNSRQA YAVNRLSGMN
HSAHSWGTGR AVARIPRISG GGTSTSGAGA FGNMCRGGRM FAPTKIFRRW HRKINLHQKR
FAVVSALAAS SVPSLVMSRG HRIDNVPEVP LVVEDSIQGY EKTKEAMAFL KAIAAIDDVN
RVNDSREIRA GRGKMRNRRY VARRGPMLVM PNNKGTRAFR NIFGLDLANV SALNLLHLAP
GGHVGRFVIW TKSAFEQLDK IFGTFTEASA VKKGFTLPAP MLTNTDVTRI MQSEEVRRVL
KPKKLQAKKA SRYQTPTNGI KNRRLRLRLN PYVKRETAAA KGMRNVANRD ARRKAKMARV
TKAKKAATKS AKQ
//
