ID   A4I8R4_LEIIN            Unreviewed;      1004 AA.
AC   A4I8R4; A0A2K4Z3F6; A0A381MRV7;
DT   01-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAM71213.1};
GN   ORFNames=LINJ_33_0520 {ECO:0000313|EMBL:CAM71213.1};
OS   Leishmania infantum.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX   NCBI_TaxID=5671 {ECO:0000313|EMBL:CAM71213.1, ECO:0000313|Proteomes:UP000008153};
RN   [1] {ECO:0000313|EMBL:CAM71213.1, ECO:0000313|Proteomes:UP000008153}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JPCM5 {ECO:0000313|EMBL:CAM71213.1,
RC   ECO:0000313|Proteomes:UP000008153};
RX   PubMed=17572675; DOI=10.1038/ng2053;
RA   Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA   Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA   Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA   Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA   Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA   Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA   Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA   Mottram J.C., Smith D.F., Berriman M.;
RT   "Comparative genomic analysis of three Leishmania species that cause
RT   diverse human disease.";
RL   Nat. Genet. 39:839-847(2007).
RN   [2] {ECO:0000313|EMBL:CAM71213.1, ECO:0000313|Proteomes:UP000008153}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JPCM5 {ECO:0000313|EMBL:CAM71213.1,
RC   ECO:0000313|Proteomes:UP000008153};
RX   PubMed=22038252; DOI=10.1101/gr.122945.111;
RA   Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA   Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA   Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA   Hertz-Fowler C., Mottram J.C.;
RT   "Chromosome and gene copy number variation allow major structural change
RT   between species and strains of Leishmania.";
RL   Genome Res. 21:2129-2142(2011).
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DR   EMBL; FR796465; CAM71213.1; -; Genomic_DNA.
DR   RefSeq; XP_001468133.1; XM_001468096.1.
DR   AlphaFoldDB; A4I8R4; -.
DR   STRING; 5671.A4I8R4; -.
DR   GeneID; 5072205; -.
DR   KEGG; lif:LINJ_33_0520; -.
DR   VEuPathDB; TriTrypDB:LINF_330011600; -.
DR   eggNOG; ENOG502S1HC; Eukaryota.
DR   InParanoid; A4I8R4; -.
DR   OMA; RCFQEHY; -.
DR   OrthoDB; 122280at2759; -.
DR   Proteomes; UP000008153; Chromosome 33.
DR   CDD; cd20071; SET_SMYD; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR12197; HISTONE-LYSINE N-METHYLTRANSFERASE SMYD; 1.
DR   PANTHER; PTHR12197:SF300; SET DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00856; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008153}.
SQ   SEQUENCE   1004 AA;  107442 MW;  E0673F8978D31CEC CRC64;
     MNTAHADRRA TWDWDVASPS ATILPAGEPP LPSSAMLSSL LRLLSAVGSG LRTPPAPPST
     TSLFREGARF GDGESLCVHA SEASFLCCCL ALLVCRWVAE RVAIPSDGDL LAILRQIPSA
     PLGRGPSHPL TPFNEEADDD AREESWRRLH CSTVALADCR VSTLLPAPPP QLTRSALTAV
     LELDCDVLSD DDDRGALIDV VLSHLCAAPS LPGAAADACG GTERSVMAAL SDTWRDVKSR
     IPLKASSSVH LTGGHISALL RMYAEASVEL ASITLLRTLT AAAEPTAGAD TEIAAAVAAL
     GAVHEILGAQ QVARITASHI ASVPTDQTSL HRIRTLLLAL LGASPLSSSR AQFYLHPHLE
     LSIDPSRSVA GCGLVAIGTL GEGELLAREA ALATVAGTEV RIFCRGGSET TSAVANTEEH
     IQDSTPIWRE GVRRCHSSAA TAPVAEEAAN EPIAWTRHRK DAAPFITENG DRSAAAQLLS
     LLARFPDLLR SGLHQWVERV MRDAFAFQSA SCVQQMQASK ATKPPAEAAE QKSPCDTNIT
     AGAPLRRARS WRGGAVHASL PSVPQLLLDV RGVDEFRIEP PPRSWRHKPC NGQHGCVNAG
     LKRGDGDCGV AACASLSAND VSVKALFPFL RHLNHACVPN AILVLDRTPT HLCRSGDDGV
     VASLVALRTI ESGEEITVSY VPATTALTVS QKELSETLGF QCRCLLCTQK AALLRGHVCG
     ECGQLIYEPD IQGEPEALTS MLAAAGASKR TTVFRHEENC PHRRRTCEVH GVTEERSSAA
     AQLQRQLDDV VVRLAKGEGE GEATENARDP VVEAVRHLVD LDACVARTLL PTHFLRLRLR
     LEAFAYSTVA RGLGSTVSAE LIHLCASTLE ELEMLMPTNH PLLTGLRMYL VFSRGRHVRA
     VNAAEDLAHG TRHAECCGAV REQAALMQLP FVVDPLVHRC VVRCFQEHYV QLLRWRAELL
     SRAGEAGALM SFLARYSVEL EACGVTTAEH MELLSCMEDG AEDA
//