ID WDR37_XENTR Reviewed; 494 AA.
AC A4IIX9;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=WD repeat-containing protein 37;
GN Name=wdr37;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9Y2I8}. Nucleus
CC {ECO:0000250|UniProtKB:Q9Y2I8}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC136196; AAI36197.1; -; mRNA.
DR RefSeq; NP_001096465.1; NM_001102995.1.
DR AlphaFoldDB; A4IIX9; -.
DR SMR; A4IIX9; -.
DR STRING; 8364.ENSXETP00000029643; -.
DR PaxDb; 8364-ENSXETP00000039219; -.
DR DNASU; 100125083; -.
DR GeneID; 100125083; -.
DR KEGG; xtr:100125083; -.
DR AGR; Xenbase:XB-GENE-5740160; -.
DR CTD; 22884; -.
DR Xenbase; XB-GENE-5740160; wdr37.
DR eggNOG; KOG0300; Eukaryota.
DR HOGENOM; CLU_036428_0_0_1; -.
DR InParanoid; A4IIX9; -.
DR OrthoDB; 2874789at2759; -.
DR Proteomes; UP000008143; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19855:SF12; WD REPEAT-CONTAINING PROTEIN 37; 1.
DR PANTHER; PTHR19855; WD40 REPEAT PROTEIN 12, 37; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..494
FT /note="WD repeat-containing protein 37"
FT /id="PRO_0000345132"
FT REPEAT 154..194
FT /note="WD 1"
FT REPEAT 197..236
FT /note="WD 2"
FT REPEAT 279..318
FT /note="WD 3"
FT REPEAT 321..360
FT /note="WD 4"
FT REPEAT 365..403
FT /note="WD 5"
FT REPEAT 406..445
FT /note="WD 6"
FT REPEAT 452..493
FT /note="WD 7"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 54870 MW; 69E2FFEFFBEE4907 CRC64;
MPTESGSWAA ARQTKQKRKS HSLSIKRTNS SEQDRPGLQR EMLEGQDSKL PSSVRNTLLE
LFGQIEREFE NLYLENLELR REIDTLNDRL AVEGQAIDGA ELSKGQMKTK ASHSTSQLSQ
KLKTTYKAST SKIVSSFKTT TSRAICQLVK DYVGHRDGLW DVSVTRTQPV VLGTASADHT
ALLWSIETGK CLIKYVGHAG SVNSIKFHPT EQIALTASGD QTAHIWRYMV QLPTPQPTAD
TSISGEEEVD FSDKDENDGD GDASSDCPTV RVPLTALKSH QGVVIAADWL VGGKQAVTAS
WDRTANLYDV ETSELVHSLT GHDQELTHCC THPTQRLVVT SSRDTTFRLW DFRDPSIHSV
NVFQGHTDTV TSAVFTVGDN VVSGSDDRTV KVWDLKNMRS PIATIRTDSA INRISVSVGQ
RIIALPHDNR QVRLFDMSGV RLARLPRSNR QGHRRMVCCC AWSEDHPTCN LFTCGFDRQA
IGWNINIPAL LQEK
//
