ID HPR_GEOTN Reviewed; 200 AA.
AC A4IKT9;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 01-MAY-2013, entry version 50.
DE RecName: Full=HTH-type transcriptional regulator Hpr;
DE AltName: Full=Protease production regulatory protein Hpr;
GN Name=hpr; OrderedLocusNames=GTNG_0561;
OS Geobacillus thermodenitrificans (strain NG80-2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX NCBI_TaxID=420246;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NG80-2;
RX PubMed=17372208; DOI=10.1073/pnas.0609650104;
RA Feng L., Wang W., Cheng J., Ren Y., Zhao G., Gao C., Tang Y., Liu X.,
RA Han W., Peng X., Liu R., Wang L.;
RT "Genome and proteome of long-chain alkane degrading Geobacillus
RT thermodenitrificans NG80-2 isolated from a deep-subsurface oil
RT reservoir.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:5602-5607(2007).
CC -!- FUNCTION: Negative regulator of protease production and
CC sporulation (By similarity).
CC -!- SUBUNIT: Homodimer (By similarity).
CC -!- SIMILARITY: Contains 1 HTH marR-type DNA-binding domain.
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DR EMBL; CP000557; ABO65943.1; -; Genomic_DNA.
DR RefSeq; YP_001124688.1; NC_009328.1.
DR ProteinModelPortal; A4IKT9; -.
DR SMR; A4IKT9; 8-186.
DR STRING; 420246.GTNG_0561; -.
DR EnsemblBacteria; ABO65943; ABO65943; GTNG_0561.
DR GeneID; 4965505; -.
DR KEGG; gtn:GTNG_0561; -.
DR PATRIC; 21977407; VBIGeoThe136879_0588.
DR eggNOG; COG1846; -.
DR HOGENOM; HOG000246900; -.
DR KO; K09682; -.
DR OMA; NEHHILW; -.
DR ProtClustDB; PRK13777; -.
DR BioCyc; GTHE420246:GIXT-633-MONOMER; -.
DR GO; GO:0005622; C:intracellular; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:HAMAP.
DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:HAMAP.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:HAMAP.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:HAMAP.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR HAMAP; MF_01911; HTH-type_Hpr; 1; -.
DR InterPro; IPR023488; Tscrpt_reg_HTH_Hpr.
DR InterPro; IPR000835; Tscrpt_reg_HTH_MarR-typ.
DR InterPro; IPR023187; Tscrpt_reg_MarR-type_CS.
DR InterPro; IPR011991; WHTH_DNA-bd_dom.
DR Pfam; PF01047; MarR; 1.
DR SMART; SM00347; HTH_MARR; 1.
DR PROSITE; PS01117; HTH_MARR_1; 1.
DR PROSITE; PS50995; HTH_MARR_2; 1.
PE 3: Inferred from homology;
KW Complete proteome; DNA-binding; Repressor; Sporulation; Transcription;
KW Transcription regulation.
FT CHAIN 1 200 HTH-type transcriptional regulator Hpr.
FT /FTId=PRO_0000343631.
FT DOMAIN 13 157 HTH marR-type.
FT DNA_BIND 63 86 H-T-H motif (By similarity).
SQ SEQUENCE 200 AA; 23474 MW; 6194D7BC9BEAAAB0 CRC64;
MKSTEQHYSI KEAMLFSQRI AQLSKALWKS IEKDWQQWIK PFNLNINEHH ILWIAYHFKG
ASISEIAKFG VMHVSTAFNF SKKLEEKGLL SFSKKQDDKR NTYIELTEKG EEVLMKLMET
YDPTRNAVFN GALPLRELYG KFPEILEMMC IVRNIYGDDF MEIFERAFEN IKEDFVEQDG
KLVKRAPKAE EHEKELASPG
//
