ID A4PBS8_PHACA Unreviewed; 63 AA.
AC A4PBS8;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Metallothionein {ECO:0000256|RuleBase:RU000621};
GN Name=MT2 {ECO:0000313|EMBL:BAF51972.1};
OS Phalacrocorax carbo (Great cormorant) (Pelecanus carbo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Suliformes; Phalacrocoracidae;
OC Phalacrocorax.
OX NCBI_TaxID=9209 {ECO:0000313|EMBL:BAF51972.1};
RN [1] {ECO:0000313|EMBL:BAF51972.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=17317328; DOI=10.1016/j.cbpc.2006.10.012;
RA Nam D.H., Kim E.Y., Iwata H., Tanabe S.;
RT "Molecular characterization of two metallothionein isoforms in avian
RT species: evolutionary history, tissue distribution profile, and expression
RT associated with metal accumulation.";
RL Comp. Biochem. Physiol. C Toxicol. Pharmacol. 145:295-305(2007).
CC -!- FUNCTION: Metallothioneins have a high content of cysteine residues
CC that bind various heavy metals. {ECO:0000256|RuleBase:RU000621}.
CC -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 1 family.
CC {ECO:0000256|ARBA:ARBA00007283, ECO:0000256|RuleBase:RU000621}.
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DR EMBL; AB258229; BAF51972.1; -; mRNA.
DR AlphaFoldDB; A4PBS8; -.
DR GO; GO:0008270; F:zinc ion binding; ISS:AgBase.
DR GO; GO:0032496; P:response to lipopolysaccharide; ISS:AgBase.
DR Gene3D; 4.10.10.10; Metallothionein Isoform II; 1.
DR InterPro; IPR017854; Metalthion_dom_sf.
DR InterPro; IPR023587; Metalthion_dom_sf_vert.
DR InterPro; IPR000006; Metalthion_vert.
DR InterPro; IPR018064; Metalthion_vert_metal_BS.
DR PANTHER; PTHR23299; METALLOTHIONEIN; 1.
DR PANTHER; PTHR23299:SF63; METALLOTHIONEIN 1H-LIKE PROTEIN 1-RELATED; 1.
DR Pfam; PF00131; Metallothio; 1.
DR PRINTS; PR00860; MTVERTEBRATE.
DR SUPFAM; SSF57868; Metallothionein; 1.
DR PROSITE; PS00203; METALLOTHIONEIN_VRT; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000621};
KW Metal-thiolate cluster {ECO:0000256|ARBA:ARBA00022851,
KW ECO:0000256|RuleBase:RU000621}.
SQ SEQUENCE 63 AA; 6465 MW; B46242251463E65E CRC64;
MDPQDCTCAA GDSCSCAGSC KCKNCRCRSC RKSCCSCCPA SCSNCAKGCV CKEPASSKCS
CCH
//
