ID   A4PIW0_HUMAN            Unreviewed;       457 AA.
AC   A4PIW0;
DT   15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   15-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=Fusion protein SYT-SSX2 {ECO:0000313|EMBL:BAF56184.1};
GN   Name=SYT-SSX2 {ECO:0000313|EMBL:BAF56184.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAF56184.1};
RN   [1] {ECO:0000313|EMBL:BAF56184.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Ouchida M.;
RT   "Fusion genes in Synovial Sarcoma cells.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- INTERACTION:
CC       A4PIW0; P15336: ATF2; NbExp=11; IntAct=EBI-6050533, EBI-1170906;
CC       A4PIW0; Q04724: TLE1; NbExp=11; IntAct=EBI-6050533, EBI-711424;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the SS18 family.
CC       {ECO:0000256|ARBA:ARBA00007945}.
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DR   EMBL; AB300357; BAF56184.1; -; mRNA.
DR   AlphaFoldDB; A4PIW0; -.
DR   IntAct; A4PIW0; 13.
DR   PeptideAtlas; A4PIW0; -.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR   InterPro; IPR044779; SS18.
DR   InterPro; IPR007726; SS18_N.
DR   InterPro; IPR019041; SSXRD_motif.
DR   PANTHER; PTHR23107:SF2; PROTEIN SSXT; 1.
DR   PANTHER; PTHR23107; SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN; 1.
DR   Pfam; PF09514; SSXRD; 1.
DR   Pfam; PF05030; SSXT; 1.
PE   1: Evidence at protein level;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          14..73
FT                   /note="SS18 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05030"
FT   REGION          77..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          188..435
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..246
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..308
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        317..361
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        416..435
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   457 AA;  50106 MW;  ED4D19E02B995BBB CRC64;
     MSVAFAAPRQ RGKGEITPAA IQKMLDDNNH LIQCIMDSQN KGKTSECSQY QQMLHTNLVY
     LATIADSNQN MQSLLPAPPT QNMPMGPGGM NQSGPPPPPR SHNMPSDGMV GGGPPAPHMQ
     NQMNGQMPGP NHMPMQGPGP NQLNMTNSSM NMPSSSHGSM GGYNHSVPSS QSMPVQNQMT
     MSQGQPMGNY GPRPNMSMQP NQGPMMHQQP PSQQYNMPQG GGQHYQGQQP PMGMMGQVNQ
     GNHMMGQRQI PPYRPPQQGP PQQYSGQEDY YGDQYSHGGQ GPPEGMNQQY YPDGNSQYGQ
     QQDAYQGPPP QQGYPPQQQQ YPGQQGYPGQ QQGYGPSQGG PGPQYPNYPQ GQGQQYGGYR
     PTQPGPPQPP QQRPYGYDQI MPKKPAEEGN DSEEVPEASG PQNDGKELCP PGKPTTSEKI
     HERSGPKRGE HAWTHRLRER KQLVIYEEIS DPEEDDE
//