ID A4QNC4_XENTR Unreviewed; 664 AA.
AC A4QNC4;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Amphiphysin {ECO:0000313|RefSeq:NP_001096507.1};
DE SubName: Full=LOC100125136 protein {ECO:0000313|EMBL:AAI35396.1};
GN Name=amph {ECO:0000313|RefSeq:NP_001096507.1,
GN ECO:0000313|Xenbase:XB-GENE-993128};
GN Synonyms=LOC100125136 {ECO:0000313|EMBL:AAI35396.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI35396.1};
RN [1] {ECO:0000313|RefSeq:NP_001096507.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI35396.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole embryo {ECO:0000313|EMBL:AAI35396.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001096507.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC135395; AAI35396.1; -; mRNA.
DR RefSeq; NP_001096507.1; NM_001103037.1.
DR DNASU; 100125136; -.
DR GeneID; 100125136; -.
DR KEGG; xtr:100125136; -.
DR AGR; Xenbase:XB-GENE-993128; -.
DR CTD; 273; -.
DR Xenbase; XB-GENE-993128; amph.
DR OrthoDB; 4243832at2759; -.
DR Proteomes; UP000008143; Chromosome 6.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd07611; BAR_Amphiphysin_I_II; 1.
DR CDD; cd12140; SH3_Amphiphysin_I; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR003005; Amphiphysin.
DR InterPro; IPR003017; Amphiphysin_1.
DR InterPro; IPR035470; Amphiphysin_I_SH3.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46514; AMPHIPHYSIN; 1.
DR PANTHER; PTHR46514:SF2; AMPHIPHYSIN; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR01251; AMPHIPHYSIN.
DR PRINTS; PR01252; AMPHIPHYSIN1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..240
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 591..664
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 245..312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 152..186
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 296..310
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 74717 MW; 931298DD697E3F3A CRC64;
MADMKTGIFA KNVQKRLSRA QEKVLQKLGK ADETKDEQFE EYVQNFKRQE AEGSRLQREM
RAYLTAIKGM QEASMKLTES LHEVYEPDWY GRDDVKMVGE KCDTLWEDFH QKLVDGALIT
LDTYLGQFPD IKNRIAKRSR KLVDYDSARH HLESLQNAKR KDEGRISKAE EEFQKAQKVF
EDFNIDLQEE LPSLWSRRIG FYVNTFQNIS GLEAKFHKEI TVLCHKLYEV MTKLGEQHAD
KAFTIQGAPS DSGPLRIAKT PSPPEEVPEE PSPLASPNHT LAPISSPAPA RPKSPSQLRK
GPPVPPLPKL TPSKELQQEN IISFFEDNFV PEINVTTPSQ NEAVEEKKEE SLLDLDFDPF
KPESATVGIV QSHSPLSQTL PWDLWTTNNE VVQPASTGAF NGFTQPDASA PLFTLPLEQN
DEVVESDVAV ALEAESEETE SVTDVPAEET KLDEQTELVE KSVEVVEVDE DRAVSEAEKE
VSEIEVEVKE ESAESAAEMA DDIMEEQKEP EINEPKETEA PQEITCIPSV VIEPASNHED
EHDNDITIEV TEAVEEKFET DSTLDSTVEQ SHSVSNDEAD SLTTSQSKPE GFLYKAEALH
DFEAANEDEL NLKRGDIVIV ITSVTAADQE AGWLTGVRET DWLQHKDAEA YKGLFPENFT
RRLD
//
