ID A4S4R9_OSTLU Unreviewed; 352 AA.
AC A4S4R9;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein {ECO:0000259|Pfam:PF02826};
GN ORFNames=OSTLU_26506 {ECO:0000313|EMBL:ABO98609.1};
OS Ostreococcus lucimarinus (strain CCE9901).
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Ostreococcus.
OX NCBI_TaxID=436017 {ECO:0000313|EMBL:ABO98609.1, ECO:0000313|Proteomes:UP000001568};
RN [1] {ECO:0000313|EMBL:ABO98609.1, ECO:0000313|Proteomes:UP000001568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCE9901 {ECO:0000313|EMBL:ABO98609.1,
RC ECO:0000313|Proteomes:UP000001568};
RX PubMed=17460045; DOI=10.1073/pnas.0611046104;
RA Palenik B., Grimwood J., Aerts A., Rouze P., Salamov A., Putnam N.,
RA Dupont C., Jorgensen R., Derelle E., Rombauts S., Zhou K., Otillar R.,
RA Merchant S.S., Podell S., Gaasterland T., Napoli C., Gendler K.,
RA Manuell A., Tai V., Vallon O., Piganeau G., Jancek S., Heijde M.,
RA Jabbari K., Bowler C., Lohr M., Robbens S., Werner G., Dubchak I.,
RA Pazour G.J., Ren Q., Paulsen I., Delwiche C., Schmutz J., Rokhsar D.,
RA Van de Peer Y., Moreau H., Grigoriev I.V.;
RT "The tiny eukaryote Ostreococcus provides genomic insights into the paradox
RT of plankton speciation.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7705-7710(2007).
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DR EMBL; CP000591; ABO98609.1; -; Genomic_DNA.
DR RefSeq; XP_001420316.1; XM_001420279.1.
DR AlphaFoldDB; A4S4R9; -.
DR STRING; 436017.A4S4R9; -.
DR EnsemblPlants; ABO98609; ABO98609; OSTLU_26506.
DR GeneID; 5004370; -.
DR Gramene; ABO98609; ABO98609; OSTLU_26506.
DR KEGG; olu:OSTLU_26506; -.
DR eggNOG; KOG0068; Eukaryota.
DR HOGENOM; CLU_019796_1_0_1; -.
DR OMA; HGARNAM; -.
DR OrthoDB; 1327616at2759; -.
DR Proteomes; UP000001568; Chromosome 11.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001568}.
FT DOMAIN 140..315
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 352 AA; 38932 MW; 2636E95A422D0126 CRC64;
MTTQSATTTT ARSATTTATT TLCVVTHEKL LNSRPLTERL RAETPRAFDV VVVSNEEEID
KMRRERADGD LAMLWWFATK EVTTAFASRR DVAERVKWMH SGSAGVDHLM AIPSVREHAS
TLTNGRGAFS ASLGEWGVFA CMHFAKRVDA MRAAQRRKEW IRMTVGLIEG KKLVIVGYGD
IGQHVARRAK AMGMKVCAVR RTPEKTDPND DYVENVVGFH ALKETCAKAD YVLVALPSTE
ETDKMINADV LSAMKDTAVL INVGRGSTVD EDALVDALRN KKIAGAALDV FAVEPLPSDH
PFYTMENVLM SFHCADLTSD YHDLALDCFI KHAEQYATNA PFTNVVDKRL GY
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