ID   A4TUP2_9PROT            Unreviewed;       639 AA.
AC   A4TUP2;
DT   15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   15-MAY-2007, sequence version 1.
DT   03-MAY-2023, entry version 37.
DE   SubName: Full=Capsular polysaccharide biosynthesis protein {ECO:0000313|EMBL:CAM74349.1};
GN   Name=capD {ECO:0000313|EMBL:CAM74349.1};
GN   ORFNames=MGR_0190 {ECO:0000313|EMBL:CAM74349.1};
OS   Magnetospirillum gryphiswaldense.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Magnetospirillum.
OX   NCBI_TaxID=55518 {ECO:0000313|EMBL:CAM74349.1};
RN   [1] {ECO:0000313|EMBL:CAM74349.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MSR-1 {ECO:0000313|EMBL:CAM74349.1};
RX   PubMed=17449609; DOI=10.1128/JB.00119-07;
RA   Richter M., Kube M., Bazylinski D.A., Lombardot T., Gloeckner F.O.,
RA   Reinhardt R., Schueler D.;
RT   "Comparative genome analysis of four magnetotactic bacteria reveals a
RT   complex set of group-specific genes implicated in magnetosome
RT   biomineralization and function.";
RL   J. Bacteriol. 189:4899-4910(2007).
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; CU459003; CAM74349.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4TUP2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF13727; CoA_binding_3; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        79..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        112..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          294..581
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   639 AA;  69270 MW;  1F6E81446FA6E6AE CRC64;
     MMPRLTLHRG HIALVHDLVM AALSFLVAIF LRMDATWVPG WGPDMLVIAT ALFTAIACVS
     FLTARMYKGV WRYASVNDLL TIARGATVTV VAFYLLMFLV TRLQDLPRSV LIINWLVLLA
     LLGGPRFIYR SWKDRRRAAK QVAGAGRIPV LLAGAGDEAE LFLRATSAPD AEYRAVGLIS
     EGAGRVGRNI HGVDVLGEIG DFAGVVEQLR AKGQGPQRLI VTDDRLDGSV VRRLLDECDR
     LGLTLARIPR LTDLKDGVED KLSLRPIAVE DLLGRPQNLL DRAGVQAMLT GKRVLITGAG
     GSIGSELVRQ VAGYAPEMLA LFDAGEFNLY AIDLELAKTH PDVPRRPMLG DVRDGQRVRA
     AMAEIRPDVV FHAAALKHVP MVECNPDEGL LTNAIGTRIV ADACVEAGVR VMVQISTDKA
     VNPTNVMGAS KRVGEMYAQA LDMAGDGHTR FVTVRFGNVL GSTGSVVPLF QKQLAEGGPL
     TVTHPDMTRY FMTVREAVEL VLQASAFGLA HPDYRGKIFV LDMGEPVRIV DLARQMIRLA
     GLRPDADVKI AFTGLRPGEK LFEEIFHGSE PPMPTEAKGI LLASPRWVDR AELGGALDDL
     DIACRSHQGD RAVAIVSRLV PEYTLSAEAL ALTGATEAK
//