ID A4U1M9_9PROT Unreviewed; 830 AA.
AC A4U1M9;
DT 15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 15-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MGR_3139 {ECO:0000313|EMBL:CAM76786.1};
OS Magnetospirillum gryphiswaldense.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Magnetospirillum.
OX NCBI_TaxID=55518 {ECO:0000313|EMBL:CAM76786.1};
RN [1] {ECO:0000313|EMBL:CAM76786.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MSR-1 {ECO:0000313|EMBL:CAM76786.1};
RX PubMed=17449609; DOI=10.1128/JB.00119-07;
RA Richter M., Kube M., Bazylinski D.A., Lombardot T., Gloeckner F.O.,
RA Reinhardt R., Schueler D.;
RT "Comparative genome analysis of four magnetotactic bacteria reveals a
RT complex set of group-specific genes implicated in magnetosome
RT biomineralization and function.";
RL J. Bacteriol. 189:4899-4910(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CU459003; CAM76786.1; -; Genomic_DNA.
DR AlphaFoldDB; A4U1M9; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:CAM76786.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:CAM76786.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 598..818
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 553..584
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 830 AA; 90139 MW; 9BF0F2260B507090 CRC64;
MAGGTVVAVI LWFGLDMVQS ARTDAIIHAN VDHQLKVQAE AGQARFQAIL QNHFTYTAFL
AASAPVSDLA GQSLRFSPTE KPVDGLLSEL SLLHDPISRA DISFLAVIDG NSRIRRLMSD
GAHPPPAGLQ DFVAALPVNA AHRAIVQRLG GDVYVVSVHA IAGQRASLVV LTRWDSGLLT
RAHGFAPGSD LTVAIADMFH GVVAASSDPA VIAMGLPLIR LETDWLAVYQ ELPDHGGIDF
LPAFVTIVSH AYADRQAEPL LRQEREQRTV LAATLIGLFL LVLVVVALRL RQIIDQVALV
IESVNGKQEP AFKGGDELLG LVRQVHTLAT EVRRSRQALQ SEAAEKMRLN EERILVREEN
ARLRLLQTVT DLLRVGVVRL GHDGPVAENR AMEEMSQTCG GLSPFVQASN RGSQDLVALD
THGAERIYEL LSADGIDHDL ILVTEVTEQR RAEQMIHSLA LFPAQSPYPV LRIGIDGAIL
HANPASEPLL SEWATGMGRK VPDEWHGIIT EVLATGRQLQ AELPVIGRVL SLTLVPVKGA
GYVNIYATDV SDRVAAERQL ADANEDLERR VEERTRDLVR AKEQAELASR SKSEFLATIS
HELRTPLNAI IGFSEVMAGS MFGPLGNSRY QEYAGDIVQS GRHLLAVIND ILDVSKIEAG
QMSLDFGPVD IPPVIDSAVR LVETRARANS LRLRSEVDKD LPIIDGDRRR CLQILVNLLS
NAIKFTPEGG QVTIGASREN DGIRLKVQDT GIGMSESEIQ VALEPFRQVD GSLSRQYEGT
GLGLPLAKSM VELHGGSLVV NSRKGEGTEV AFWLPLNQNS GKGLGPNWDI
//
