ID   A4U9Y5_9GAMM            Unreviewed;       179 AA.
AC   A4U9Y5;
DT   15-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   15-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase {ECO:0000313|EMBL:ABF70986.1};
DE   Flags: Fragment;
OS   Moraxella bovoculi.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Moraxella.
OX   NCBI_TaxID=386891 {ECO:0000313|EMBL:ABF70986.1};
RN   [1] {ECO:0000313|EMBL:ABF70986.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=237 {ECO:0000313|EMBL:ABF70986.1};
RX   PubMed=17392208; DOI=10.1099/ijs.0.64333-0;
RA   Angelos J.A., Spinks P.Q., Ball L.M., George L.W.;
RT   "Moraxella bovoculi sp. nov., isolated from calves with infectious bovine
RT   keratoconjunctivitis.";
RL   Int. J. Syst. Evol. Microbiol. 57:789-795(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) +
CC         NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378, ChEBI:CHEBI:57318,
CC         ChEBI:CHEBI:57540, ChEBI:CHEBI:57945, ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|ARBA:ARBA00023693};
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DR   EMBL; DQ647935; ABF70986.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4U9Y5; -.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43612:SF8; FATTY ACID OXIDATION COMPLEX SUBUNIT ALPHA; 1.
DR   PANTHER; PTHR43612; TRIFUNCTIONAL ENZYME SUBUNIT ALPHA; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          151..179
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABF70986.1"
FT   NON_TER         179
FT                   /evidence="ECO:0000313|EMBL:ABF70986.1"
SQ   SEQUENCE   179 AA;  19009 MW;  78E6B5D6A122C65B CRC64;
     IATGNSLRPA DALKVGLVDA VVADDILEQS AIDLVHKCIS GEIDWQAKRA EKLEPVKLNK
     TEQAMAFNSA KGVIFAKANP KHYPSIALAL DAVERHANLG RDEAIKIEAT NFAKSAKTPQ
     AGALVGVFLN DQLVKKRAKE QSKSAHDIDE MAVLGAGIMG GGIAYQSAVK GLPIIMKDI
//