ID A4V9W6_DROSI Unreviewed; 503 AA.
AC A4V9W6;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=CG9649 protein {ECO:0000313|EMBL:CAL85489.1};
GN Name=CG9649 {ECO:0000313|EMBL:CAL85489.1};
OS Drosophila simulans (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7240 {ECO:0000313|EMBL:CAL85489.1};
RN [1] {ECO:0000313|EMBL:CAL85489.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KY215 {ECO:0000313|EMBL:CAL85489.1};
RX PubMed=17465907; DOI=10.1111/j.1420-9101.2007.01305.x;
RA Jiggins F.M., Kim K.W.;
RT "A screen for immunity genes evolving under positive selection in
RT Drosophila.";
RL J. Evol. Biol. 20:965-970(2007).
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DR EMBL; AM412866; CAL85489.1; -; Genomic_DNA.
DR AlphaFoldDB; A4V9W6; -.
DR MEROPS; S01.A44; -.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR031986; GD_N.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR PANTHER; PTHR24260; -; 1.
DR PANTHER; PTHR24260:SF153; GH19262P-RELATED; 1.
DR Pfam; PF16030; GD_N; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..503
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002673927"
FT DOMAIN 256..502
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT REGION 170..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..208
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 503 AA; 56352 MW; B9B86559924BF22D CRC64;
MRQLQLLGFL IAVLQISYIS AQHLPYIQCP MIFRYLEYEN QFIGHLQLIL DSTNTDNVVR
VELSQPGRNT PSTPGTLNFL EDEDSLRHRL TNNEPINYRI DFPTPGVVPK LTKVTVNGKV
ACEAAPFRAP STRLTLSRTL RTTVPLAAIP PSQRTDHQWP QAPQTNYTVY EEEEEEPVQR
RRPQQSPPRP RPQQPPSRPR PQPVPQLPQE PKFQTSARPS VLPSNPPAQV SKSYPQTIGQ
LSGICGREKV IQTPFIHNGI EVERGQLPWM AALFEHVGRD YNFLCGGTLI SARTVISAAH
CFRFGSRNLP GERTIVSLGR NSLDLFSSGA TVGVARLLIH EQYNPNVYTD ADLALLQLAN
HVDIGDYIKP ICLWNENFLL ELPSGHKSYV AGWGEDEKGN RNTRLAKMTD TDIITQWECR
GNLSEENAKF ITSHTICASN AQASGPCSGD SGGGLMLQEQ DIWMLRGVVS AGQRMTNRCN
LTLPVIYTDV AKHIEWLVSS MWF
//
