ID A4XID8_CALS8 Unreviewed; 1066 AA.
AC A4XID8;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Stage 0 sporulation protein A homolog {ECO:0000256|ARBA:ARBA00018672};
GN OrderedLocusNames=Csac_1059 {ECO:0000313|EMBL:ABP66673.1};
OS Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T
OS 6331).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=351627 {ECO:0000313|EMBL:ABP66673.1, ECO:0000313|Proteomes:UP000000256};
RN [1] {ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A.,
RA VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J.,
RA Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M.,
RA Kengen S.M.W., Richardson P.;
RT "Genome sequence of the thermophilic hydrogen-producing bacterium
RT Caldicellulosiruptor saccharolyticus DSM 8903.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP66673.1, ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RX PubMed=18776029; DOI=10.1128/AEM.00968-08;
RA van de Werken H.J., Verhaart M.R., VanFossen A.L., Willquist K.,
RA Lewis D.L., Nichols J.D., Goorissen H.P., Mongodin E.F., Nelson K.E.,
RA van Niel E.W., Stams A.J., Ward D.E., de Vos W.M., van der Oost J.,
RA Kelly R.M., Kengen S.W.;
RT "Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor
RT saccharolyticus.";
RL Appl. Environ. Microbiol. 74:6720-6729(2008).
CC -!- FUNCTION: May play the central regulatory role in sporulation. It may
CC be an element of the effector pathway responsible for the activation of
CC sporulation genes in response to nutritional stress. Spo0A may act in
CC concert with spo0H (a sigma factor) to control the expression of some
CC genes that are critical to the sporulation process.
CC {ECO:0000256|ARBA:ARBA00024867}.
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DR EMBL; CP000679; ABP66673.1; -; Genomic_DNA.
DR RefSeq; WP_011916620.1; NC_009437.1.
DR AlphaFoldDB; A4XID8; -.
DR STRING; 351627.Csac_1059; -.
DR KEGG; csc:Csac_1059; -.
DR eggNOG; COG2201; Bacteria.
DR HOGENOM; CLU_288498_0_0_9; -.
DR OrthoDB; 9803970at2; -.
DR Proteomes; UP000000256; Chromosome.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd17542; REC_CheY; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR44591:SF27; PROTEIN-GLUTAMATE METHYLESTERASE_PROTEIN-GLUTAMINE GLUTAMINASE 1; 1.
DR PANTHER; PTHR44591; STRESS RESPONSE REGULATOR PROTEIN 1; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT DOMAIN 2..117
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 133..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 106..133
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 133..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 52
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1066 AA; 121972 MW; F5812F926376E7B3 CRC64;
MKILIVDDAV FIRKVLRGIL QELGEEVVGE ASSGNEALRM VKEYRPDVVT LDITLPDMSG
LELLKKIKEV SSSTQVVMIT AISNHEVVKE AMKVGATNYI TKPFSREKVE EVLKKVEKNI
QAMSQIERNM TNEESIGQKE LSQATIETPG VENESKNEEV ARIDEFVKVE GEGGKSKVDT
TEISDVPELT QDLSEKRNET NNQQEISEKV SDLIETKMGV SDEFLEDEKE KEGSTTSVFY
DEDKGEEIDV GGIVTNIEFE QKGGEDILSI CTNKEIAYNV GRMKLGNGVI VTIEECFVAS
NVKHEYTFEN SLVEKVEVKE INGNVYIMVL TKAKKFDIRE REGKISIVLR RSKGVISYNK
NNKFIMIDNV VPSSIQVDAI SEKEYTIRIS TSDIIFNEGE TKVEDLIVDR YIVEKSEKGY
DVKVILYKEA RHEIIEGRTS VGIKFVEVNI LKDILIHHSD EETLIELVTN SSTVPVVLEH
DTENGVAYAY LHGYIVAKTL LERNFEFEEE YLESLKIVED REKGQSYLVI CSPVKRISVV
KEKGRTFISI KPNKAFVLYN LFQECIVFQN ILPEEIEINH NQIQNTIEFH VNNKYVNLLK
DPILNSEQFE AFSSIEIERV GKGYSGTIVL KNKSKIEVAL SKDRTSTNLF IIPYRKLNKI
KAFEYEENGP KASLTLKGEG EIKYLAERDK EKGAVTIKVL TASLCNIEQP IVEFREGCIE
RVEFYEQEED VIINIYSKVE DFNVRLENSN IIVEFEAQVV TVNPVIEDDM VVFELSRIDY
DDVEVIKDDE NNMLIVKIRR RDIYIEKGIK YLQSKVVKRY QVAQENGYKL LIDTADQVRY
SVEKKEDKIF LTVEKCPVLE KVEVKEVNEE LVHVEFHFNR GGIKPQKVEK EDGKLNVLLG
EVLTKEKDIV WNTKSRKVVK SIDYISSEKV LILSIEHAYA FWQVVVENNV IKLIFEVKHC
EILVEDEYIK IQNVESNKVQ ILKFEDNGLL IAIIPQSAAF VTSNSLKLTS NNVLYSAIEQ
DINQTEWKVY VLYKPNMMFE SEIDNNDVMI KITSKRNNFA ESELGT
//
