ID A4XII0_CALS8 Unreviewed; 604 AA.
AC A4XII0;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Histidine kinase internal region {ECO:0000313|EMBL:ABP66715.1};
GN OrderedLocusNames=Csac_1103 {ECO:0000313|EMBL:ABP66715.1};
OS Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T
OS 6331).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=351627 {ECO:0000313|EMBL:ABP66715.1, ECO:0000313|Proteomes:UP000000256};
RN [1] {ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A.,
RA VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J.,
RA Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M.,
RA Kengen S.M.W., Richardson P.;
RT "Genome sequence of the thermophilic hydrogen-producing bacterium
RT Caldicellulosiruptor saccharolyticus DSM 8903.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP66715.1, ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RX PubMed=18776029; DOI=10.1128/AEM.00968-08;
RA van de Werken H.J., Verhaart M.R., VanFossen A.L., Willquist K.,
RA Lewis D.L., Nichols J.D., Goorissen H.P., Mongodin E.F., Nelson K.E.,
RA van Niel E.W., Stams A.J., Ward D.E., de Vos W.M., van der Oost J.,
RA Kelly R.M., Kengen S.W.;
RT "Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor
RT saccharolyticus.";
RL Appl. Environ. Microbiol. 74:6720-6729(2008).
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DR EMBL; CP000679; ABP66715.1; -; Genomic_DNA.
DR RefSeq; WP_011916661.1; NC_009437.1.
DR AlphaFoldDB; A4XII0; -.
DR STRING; 351627.Csac_1103; -.
DR KEGG; csc:Csac_1103; -.
DR eggNOG; COG2972; Bacteria.
DR HOGENOM; CLU_020473_6_1_9; -.
DR Proteomes; UP000000256; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABP66715.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 317..370
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT COILED 344..390
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 604 AA; 70863 MW; 4B22670D5DAAF2C5 CRC64;
MSFSKKLFLA YSLLIIFLAF IVGIAFYTYN LRVMEEDVVA KLNAVSDKVA QEVSSLLNQM
DFIIDFLISN NDFVESTITL NALNRKNNSN LVYVNEAKKT IEGILYNYLI IRRFYRVSYF
NKKGDFITSN FKSPFPQEDR VNQLINKTKW FTLSEKVQGN IIIPQYYDPW RDDKNVKVFS
KVRFLGGYEN GLGYIEVQML YSNIENIFND ESLKNVKILM TADKNVFYAR NISETEMKDY
YKLLSKFTNV EIDFSSLDKN DNELIAIRYL PKQKIAIFLI FDRTLIERPL KISRNSVLLF
GLLIIFISLF FIYFMTNQFT KPIRELKSKV DKININNLSQ RIVLENTNDE IKALNKAFQN
LLDRLNEAIN KEMKYKLLQM KANLEALQAQ VNPHFIYNIL NIISHRGLLN KDKEICEICS
SLASMLRYST SASSRIATLK DEVEHVRNYL NLMKKRYEDK LEYFMEFQEE VLNQRVPKLI
LQPIVENSFA HGFENKTDKM KVWIKGYEKD NWWYVEVKDN GQGFDDEALI NIKREIENIK
RSFNYNEEIE GFEIGKIGLL NTYARMMIFY KNKFVFDIGN SNENGGAVVL LGGEIEVNRE
EGER
//
