ID A4XIQ5_CALS8 Unreviewed; 354 AA.
AC A4XIQ5;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Bifunctional phosphoglucose/phosphomannose isomerase {ECO:0000313|EMBL:ABP66790.1};
DE EC=5.3.1.8 {ECO:0000313|EMBL:ABP66790.1};
GN OrderedLocusNames=Csac_1187 {ECO:0000313|EMBL:ABP66790.1};
OS Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T
OS 6331).
OC Bacteria; Bacillota; Clostridia; Caldicellulosiruptorales;
OC Caldicellulosiruptoraceae; Caldicellulosiruptor.
OX NCBI_TaxID=351627 {ECO:0000313|EMBL:ABP66790.1, ECO:0000313|Proteomes:UP000000256};
RN [1] {ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Lykidis A., van de Werken H.J.G., Verhaart M.R.A.,
RA VanFossen A.L., Lewis D.L., Nichols J.D., Goorissen H.P., van Niel E.W.J.,
RA Stams F.J.M., Willquist K.U., Ward D.E., van der Oost J., Kelly R.M.,
RA Kengen S.M.W., Richardson P.;
RT "Genome sequence of the thermophilic hydrogen-producing bacterium
RT Caldicellulosiruptor saccharolyticus DSM 8903.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABP66790.1, ECO:0000313|Proteomes:UP000000256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43494 / DSM 8903 / Tp8T 6331
RC {ECO:0000313|Proteomes:UP000000256};
RX PubMed=18776029; DOI=10.1128/AEM.00968-08;
RA van de Werken H.J., Verhaart M.R., VanFossen A.L., Willquist K.,
RA Lewis D.L., Nichols J.D., Goorissen H.P., Mongodin E.F., Nelson K.E.,
RA van Niel E.W., Stams A.J., Ward D.E., de Vos W.M., van der Oost J.,
RA Kelly R.M., Kengen S.W.;
RT "Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor
RT saccharolyticus.";
RL Appl. Environ. Microbiol. 74:6720-6729(2008).
CC -!- SIMILARITY: Belongs to the PGI/PMI family.
CC {ECO:0000256|ARBA:ARBA00010523}.
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DR EMBL; CP000679; ABP66790.1; -; Genomic_DNA.
DR RefSeq; WP_011916726.1; NC_009437.1.
DR AlphaFoldDB; A4XIQ5; -.
DR STRING; 351627.Csac_1187; -.
DR KEGG; csc:Csac_1187; -.
DR eggNOG; COG2222; Bacteria.
DR HOGENOM; CLU_059687_0_0_9; -.
DR OrthoDB; 9771734at2; -.
DR Proteomes; UP000000256; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:InterPro.
DR GO; GO:0004476; F:mannose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05017; SIS_PGI_PMI_1; 1.
DR CDD; cd05637; SIS_PGI_PMI_2; 1.
DR InterPro; IPR019490; Glu6P/Mann6P_isomerase_C.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035484; SIS_PGI/PMI_1.
DR NCBIfam; TIGR02128; G6PI_arch; 1.
DR Pfam; PF10432; bact-PGI_C; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:ABP66790.1}.
FT DOMAIN 37..179
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 354 AA; 39483 MW; 2104A117266840D6 CRC64;
MLNNLEMIVQ NDPSGMFQAV YNLPEQIQKA YEIGKNISVD IKAEDIDKVV ITGLGGSAIG
GNLVRVFVID QCKVPVIVNR DYVLPVYVNS KTLVIASSYS GNTEETLSAY QDAKTKGAKI
IAITTGGKLK EMAEKDGYYV ITIPGGLQPR AALGYSFIPL LMLFVKIGLI PPVDDQIEET
IKVLSDLRER YKPEVPEEKN LAKRLTLKLW NKLPIIYGIS GTTEVIAERW KGQICENSKS
PAYFNVFSEL NHNEIVGTES PKHILGLFEI VMLHDIEDHK RNAIRMDITK DLVKGIVSGV
NDIYSIGNSR LARMFSLIYL GDYVSLYLAT LYQNDPTPVK KIDILKNKLA EIKD
//
