ID A4Y0T1_PSEMY Unreviewed; 765 AA.
AC A4Y0T1;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE RecName: Full=Diguanylate cyclase DosC {ECO:0000256|ARBA:ARBA00015125};
DE AltName: Full=Direct oxygen-sensing cyclase {ECO:0000256|ARBA:ARBA00029839};
GN OrderedLocusNames=Pmen_4450 {ECO:0000313|EMBL:ABP87197.1};
OS Pseudomonas mendocina (strain ymp).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=399739 {ECO:0000313|EMBL:ABP87197.1};
RN [1] {ECO:0000313|EMBL:ABP87197.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ymp {ECO:0000313|EMBL:ABP87197.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Kiss H., Brettin T., Detter J.C., Bruce D., Han C.,
RA Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Hersman L., Dubois J., Maurice P., Richardson P.;
RT "Complete sequence of Pseudomonas mendocina ymp.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000680; ABP87197.1; -; Genomic_DNA.
DR AlphaFoldDB; A4Y0T1; -.
DR STRING; 399739.Pmen_4450; -.
DR KEGG; pmy:Pmen_4450; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_50_6; -.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd01068; globin_sensor; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR044398; Globin-sensor_dom.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR039379; Protoglobin_sensor_dom.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF11563; Protoglobin; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF46458; Globin-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134}.
FT DOMAIN 191..263
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 267..318
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 351..483
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 488..747
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 765 AA; 85962 MW; 984A3EA5BB00F86F CRC64;
MARRGAFFCA EEKHEADMGN EEEFQELLQH IAPDPHELSQ RQRFLNWSQI DNERLARHAP
RLERANRQFI DALYERLAQY PAPAAILDDP ATTARLKHSQ CDYYRRLWHS PLDQAYVLER
LRIGWVHQHV GVDLKWYLGA YRMYLDGMLE ALLEPSPASD CFASLIKKVF FDIGLALDSY
GAAQRKALQD SEARYARAMR GANDGLWEWQ LEQDQLYLSE RWTSMLGLDR DSLAPTSRSW
FSRVHGDDLP GLRQAIDNHL RGLSPTLHHE YRIRRRDGSY LWVLVRGVAE TCSGGVRRIA
GSQSDISQRR AAQEQLHHAA RHDPLTGLAN RARLGELLQQ ALQRQQRPGA REAALLFIDL
DRFKLINDSL GHQIGDRVLV EVAERLSHCL RPGDHLARFG GDEFVALLDD LACMGDAERV
AQRMLDSLHP PLRLQEQTLA VTASIGIAAL QERGHPLDPL QAADLALYRA KSAGKAQFAR
YSSELQQQAQ RQLELQNALA QACSCGELRL VYQPICRLDQ GQPVLMGVEA LLRWQHDGRE
ISPLEFIPCL EESGEILAVG DWVLRQACTQ VRAWQLAGQT QLRCSVNLSS RQLQQGDFAA
RVADVLRETG LPAASLVLEI TESQLMQDSA QNLACLRELA SLGVQLALDD FGTGYSSLGY
LKRFPLHIIK VDKSFIAGTP QDAESLAISR AIIGLGHSLG LTVVAEGVEQ QAQIDFLGRE
GCLYAQGYWF SRPRSPDDLQ RLFSGEDCFD GLWCLLDASP QAVRP
//
