ID   A4YFT7_METS5            Unreviewed;       641 AA.
AC   A4YFT7;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=5-oxoprolinase (ATP-hydrolyzing) {ECO:0000313|EMBL:ABP95289.1};
DE            EC=3.5.2.9 {ECO:0000313|EMBL:ABP95289.1};
GN   OrderedLocusNames=Msed_1127 {ECO:0000313|EMBL:ABP95289.1};
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP95289.1, ECO:0000313|Proteomes:UP000000242};
RN   [1] {ECO:0000313|EMBL:ABP95289.1, ECO:0000313|Proteomes:UP000000242}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC   {ECO:0000313|Proteomes:UP000000242};
RX   PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
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DR   EMBL; CP000682; ABP95289.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4YFT7; -.
DR   STRING; 399549.Msed_1127; -.
DR   KEGG; mse:Msed_1127; -.
DR   eggNOG; arCOG01511; Archaea.
DR   HOGENOM; CLU_002157_1_2_2; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0017168; F:5-oxoprolinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABP95289.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000242}.
FT   DOMAIN          4..176
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          195..475
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          525..635
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
SQ   SEQUENCE   641 AA;  70533 MW;  C85B12C0E5B506EE CRC64;
     MECRVAIDVG GTFTDFIALV NGEIVTVKTL TNPTRPSQVI KDVLSSLGCE VTEVVHATTL
     ATNALLGQEK LDLPRTALLT TRSFRDVIEI GRQNRPRLYD LNFEKPRQLV PRELRVEVQE
     RVDAQGNILE RVEESEIEKI AQNLRERGVE SVAISYLHSY LNPTNEIRTG EVLSRHFRFV
     SLSSEVAPEP REYERTSTTV VNAVLMPLIS SYLQELNFLP SFLVMSSSGG LVDVEEASRK
     PVQLVESGPA AGVIASASLF PGNVISFDMG GTTAKAGVVI DGKFEITTEY EVGGEVHHGR
     VVKGSGYPVR FPFVDLAEVS AGGGTVIWRD DAGALRVGPL SAGADPGPMC YGRGGDKPTV
     TDANLVLGRV GEVIGGGMRL KPELARKGLS RLGDLEDVSR DALALVNLEM ARAIRLVTVE
     RGLDPSSFSL VAFGGAGPQH AVYLAEELGI SKVLIPPYPG LFSALGLLLA DWRFEARKSF
     PRDLEAEFVK LERELYDRLK GKVGHFLRYA DVRYQGQGWE LTVPVNDVNE IRQVFEEKHL
     STYGFVMSDR EIEVVTIRVF AVRRRPLPQL SVVSGQGDSP VKRRKALLED EWGEVDVYVR
     EKLRRGVRVR GPAIIEEFSS TTVVKDGWEA LVDESITLVR P
//