ID A4YGJ5_METS5 Unreviewed; 338 AA.
AC A4YGJ5;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Zn-dependent protease-like protein {ECO:0000313|EMBL:ABP95547.1};
GN OrderedLocusNames=Msed_1389 {ECO:0000313|EMBL:ABP95547.1};
OS Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS / TH2).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP95547.1, ECO:0000313|Proteomes:UP000000242};
RN [1] {ECO:0000313|EMBL:ABP95547.1, ECO:0000313|Proteomes:UP000000242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC {ECO:0000313|Proteomes:UP000000242};
RX PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT archaeon Metallosphaera sedula provides insights into bioleaching-
RT associated metabolism.";
RL Appl. Environ. Microbiol. 74:682-692(2008).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP000682; ABP95547.1; -; Genomic_DNA.
DR AlphaFoldDB; A4YGJ5; -.
DR STRING; 399549.Msed_1389; -.
DR KEGG; mse:Msed_1389; -.
DR eggNOG; arCOG00323; Archaea.
DR HOGENOM; CLU_757837_0_0_2; -.
DR Proteomes; UP000000242; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF0; METALLOPROTEASE SLR0863; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ABP95547.1};
KW Protease {ECO:0000313|EMBL:ABP95547.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000242}.
FT DOMAIN 144..299
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 338 AA; 38569 MW; A4AE4881B1195D6A CRC64;
MKISVRQESI IKERKGSNSL IYTKSIEWSV TRYLTDSGWS SSGKDQKPEP LCSSFTHPSL
AKWERAREIL ERIQSGDRIE IRKVRREIMW DDYSCLEEKI VNFVKSEDRE FAFTGDPMDI
PSVLEFLKEE TGFKPTPTFV EKGRMILDPE ATSHLLQALM SMLRANSPLL NKDERGLPDI
TVYDDPLIPY SHVYYTFDDE GVKTERKELI GNGEILNYLG TLYTGSPGNG RGMYPQPDFF
NAVLKPGDWK FRELMEESRN AFVVLGATRS EIVKKSVRIK PRKVVQLGGG EVLVREIAIP
LSELSTLDAI TSDTRFVYLD EDHGALAPFV RLTARLLF
//
