ID A4YGW8_METS5 Unreviewed; 405 AA.
AC A4YGW8;
DT 29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Transposase, IS605 OrfB family {ECO:0000313|EMBL:ABP95670.1};
DE EC=2.1.1.37 {ECO:0000313|EMBL:ABP95670.1};
GN OrderedLocusNames=Msed_1513 {ECO:0000313|EMBL:ABP95670.1};
OS Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS / TH2).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Metallosphaera.
OX NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP95670.1, ECO:0000313|Proteomes:UP000000242};
RN [1] {ECO:0000313|EMBL:ABP95670.1, ECO:0000313|Proteomes:UP000000242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC {ECO:0000313|Proteomes:UP000000242};
RX PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT archaeon Metallosphaera sedula provides insights into bioleaching-
RT associated metabolism.";
RL Appl. Environ. Microbiol. 74:682-692(2008).
CC -!- SIMILARITY: In the C-terminal section; belongs to the transposase 35
CC family. {ECO:0000256|ARBA:ARBA00008761}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the transposase 2
CC family. {ECO:0000256|ARBA:ARBA00011044}.
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DR EMBL; CP000682; ABP95670.1; -; Genomic_DNA.
DR AlphaFoldDB; A4YGW8; -.
DR STRING; 399549.Msed_1513; -.
DR KEGG; mse:Msed_1513; -.
DR eggNOG; arCOG00684; Archaea.
DR HOGENOM; CLU_032903_0_1_2; -.
DR Proteomes; UP000000242; Chromosome.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR InterPro; IPR010095; Cas12f1-like_TNB.
DR InterPro; IPR001959; Transposase.
DR InterPro; IPR021027; Transposase_put_HTH.
DR NCBIfam; NF040570; guided_TnpB; 1.
DR NCBIfam; TIGR01766; IS200/IS605 family accessory protein TnpB-like domain; 1.
DR PANTHER; PTHR30405:SF20; RNA-GUIDED DNA ENDONUCLEASE INSQ-RELATED; 1.
DR PANTHER; PTHR30405; TRANSPOSASE; 1.
DR Pfam; PF12323; HTH_OrfB_IS605; 1.
DR Pfam; PF01385; OrfB_IS605; 1.
DR Pfam; PF07282; OrfB_Zn_ribbon; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:ABP95670.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000000242};
KW Transferase {ECO:0000313|EMBL:ABP95670.1};
KW Transposition {ECO:0000256|ARBA:ARBA00022578};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 9..53
FT /note="Transposase putative helix-turn-helix"
FT /evidence="ECO:0000259|Pfam:PF12323"
FT DOMAIN 164..275
FT /note="Probable transposase IS891/IS1136/IS1341"
FT /evidence="ECO:0000259|Pfam:PF01385"
FT DOMAIN 291..359
FT /note="Cas12f1-like TNB"
FT /evidence="ECO:0000259|Pfam:PF07282"
FT REGION 386..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 225..252
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 405 AA; 47014 MW; EA5B7C5278234560 CRC64;
MKSKGNKVTL SFKYRAYPTP EVERKLINTM EIEAKVYNKL LNYIAERRKQ GIKVTQLDTQ
KLLKDMDEKH EVYSKALQMV NNVLWYNINA LAKLKRNGKK IGKLRHKKAF KIVWYNQSGF
KLQGDKLHLS KIGEIKLLLH RPIQGEVKGV ILKRSKTNKW YAIFQVEQEK QPLERTGRVV
GIDLGVEKFV TTSDGDVIEN PKLLDRREER IKLLQRRLSR KRRGSRNYEK ARAKLAMAYE
RLENTLNDYI HKITTWLVKD HDVIVVEKLN TREMVQDSLG RLRKHILYSS FSTFLHHLSY
KAERAGRRVV EVDPAYTSQT CSRCGYRVKL SLSDRVFRCP SCGLVIDRDY NASLNILKRG
VGTAPLPVEG EPLLFTFHEV VYSKFPQRSR KSSPRGGDAP SVRAE
//
