ID   A4YI02_METS5            Unreviewed;       705 AA.
AC   A4YI02;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   RecName: Full=V-type ATP synthase subunit I {ECO:0000256|ARBA:ARBA00020764, ECO:0000256|RuleBase:RU361189};
GN   OrderedLocusNames=Msed_1914 {ECO:0000313|EMBL:ABP96054.1};
OS   Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
OS   / TH2).
OC   Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Metallosphaera.
OX   NCBI_TaxID=399549 {ECO:0000313|EMBL:ABP96054.1, ECO:0000313|Proteomes:UP000000242};
RN   [1] {ECO:0000313|EMBL:ABP96054.1, ECO:0000313|Proteomes:UP000000242}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2
RC   {ECO:0000313|Proteomes:UP000000242};
RX   PubMed=18083856; DOI=10.1128/AEM.02019-07;
RA   Auernik K.S., Maezato Y., Blum P.H., Kelly R.M.;
RT   "The genome sequence of the metal-mobilizing, extremely thermoacidophilic
RT   archaeon Metallosphaera sedula provides insights into bioleaching-
RT   associated metabolism.";
RL   Appl. Environ. Microbiol. 74:682-692(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; CP000682; ABP96054.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4YI02; -.
DR   STRING; 399549.Msed_1914; -.
DR   KEGG; mse:Msed_1914; -.
DR   eggNOG; arCOG04138; Archaea.
DR   HOGENOM; CLU_025558_0_0_2; -.
DR   Proteomes; UP000000242; Chromosome.
DR   GO; GO:0033179; C:proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   Gene3D; 1.20.1460.20; -; 1.
DR   Gene3D; 3.30.70.2170; -; 1.
DR   Gene3D; 3.30.70.2750; -; 1.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR   PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000242};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM        345..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        388..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        466..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        501..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        554..572
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        613..637
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        649..672
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   COILED          90..124
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   705 AA;  78638 MW;  2C484E69FF786981 CRC64;
     MIFPENMVKV EIISPVNQKD KVTTEILKFG KMEVIEPAHP ISNSRYEDAR RELTAIQEHV
     NKVKLIMEIA GTPLEPRGKM KVDSTWTDVA KKLSEEASLE EFRYKELLEE IGKLKGEIDL
     YQAQLRELEP FSGITTDLST LYSLETLDVA LVVLTEDQLN KVKSNKNVVV ETTPLKDGKY
     ASVLISRRNV VSLDQVLKEL GVRRFETNEG KSPYEVYKVL SERIGELRKI LEETRSSLIK
     KIRENEREFS ELYGKLLTAR DALSLLSKGR ISDHFFQIEG YVPERDWKKL KSALDQVAVI
     ESATPRRFGE EEEPPTYIRL PKSISAIESV VEIYGTPSYW EISPLVFLVI TFPLLFGLMF
     PDVGNALVLL IFAIFFHRYG VKKGSNNIKN LSLILGYSSV VAMITGFLAR DFFGPLPVGG
     LKEMGIANVS GPLDSVWPVP VSVTEALSPL LPFGEYSTST SIEHTIILSI LLGAIALFVS
     SLLGVINAVK KRDPEFLVFE KLPLLVLYTV PLVIFGYGVT DPSHYFSTVG VLLGDILQNL
     LSGIHPDLSN PTSALAYGLI VWVEIGLIYN WISKAIILKR HDHASTGSAL AMGFIEGGFE
     AAILLLSNTI SFIRILVFAL AHYYLLYAFS YMAYLVVGHP SLLALGTNPA SIVILIIGNL
     LAIGLEGLVV FIQDMRLHFY EMFSKFYEGR GKKFEPLVAS VELAT
//